Sarcomatoid carcinoma of the lung

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Sarcomatoid carcinoma of the lung is a rare epithelial derived lung malignancy that has morphologic features suggestive of a malignant mesenchymal tumour (sarcoma).^[1] It is a sarcoma-like lung carcinoma.

General

Rare.^[1]
Associated with smoking.^[1]

Gross

Mass lesion - typically upper lobe and peripheral location.^[1]

Microsopic

Subclassified as:^[1]

Pleomorphic carcinoma.
Spindle cell carcinoma.
Giant cell carcinoma.
Carcinosarcoma.
Pulmonary blastoma.

DDx:

Poorly differentiated lung carcinoma (non-small cell lung carcinoma).
Primary lung sarcoma.
Metastatic disease:
- Carcinosarcoma.
- Poorly differentiated carcinoma.
- Sarcoma.

Images

ASC with SC - intermed. mag. (WC)
ASC with SC - high mag. (WC)
ASC with SC - very high mag. (WC)
ASC with SC - very high mag. (WC)

AdCa and SC (in ASC) - intermed. mag. (WC)
AdCa and SC (in ASC) - intermed. mag. (WC)
AdCa and SC (in ASC) - very high mag. (WC)

See also

References

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Franks, TJ.; Galvin, JR. (Jan 2010). "Sarcomatoid carcinoma of the lung: histologic criteria and common lesions in the differential diagnosis.". Arch Pathol Lab Med 134 (1): 49-54. doi:10.1043/2008-0547-RAR.1. PMID 20073605.

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Lung tumours