Paired box gene 5

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Paired box gene 5
Immunostain in short

PAX5 staining in a classical Hodgkin's lymphoma
Abbreviation PAX5
Use B-cell marker, weakly positive in classical Hodgkin's lymphoma
Subspeciality hematopathology
Normal staining pattern nuclear stain
Positive B-cell lymphoma, classical Hodgkin's lymphoma

Paired box gene 5, commonly known by the abbreviation PAX5, is a immunostain used in hematopathology.

Tumours with positive staining

  • B-cell lymphomas
  • Hodgkin lymphoma
    • typically weak in classical Hodgkin's lymphoma
    • strong in nodular lymphocyte-predominant Hodgkin's lymphoma

Negative staining

  • Plasmablastic neoplasms

See also