Oncogene

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An oncogene is a cancer gene, derived from a proto-oncogene.

Examples

Gene Cancer
EGFR[1] lung adenocarcinoma, glioblastoma,[2] anaplastic astrocytoma[2]
PDGFB[3] dermatofibrosarcoma protuberans
BRAF[4] papillary thyroid carcinoma tall cell variant
KRAS[5] invasive ductal carcinoma of the pancreas
MYC[6] Burkitt lymphoma
MET[7] papillary renal cell carcinoma
ERBB2 (HER2)[8] invasive breast carcinoma
CCND1 (BCL1)[9] mantle cell lymphoma
EWSR1[10] Ewing sarcoma, clear cell sarcoma, DSRCT, EMC

See also

References

  1. ↑ Online 'Mendelian Inheritance in Man' (OMIM) 131550
  2. ↑ 2.0 2.1 Lefkowitch, Jay H. (2006). Anatomic Pathology Board Review (1st ed.). Saunders. pp. 419 Q6. ISBN 978-1416025887.
  3. ↑ Online 'Mendelian Inheritance in Man' (OMIM) 190040
  4. ↑ Online 'Mendelian Inheritance in Man' (OMIM) 164757
  5. ↑ Online 'Mendelian Inheritance in Man' (OMIM) 190070
  6. ↑ Online 'Mendelian Inheritance in Man' (OMIM) 190080
  7. ↑ Online 'Mendelian Inheritance in Man' (OMIM) 164860
  8. ↑ Online 'Mendelian Inheritance in Man' (OMIM) 164870
  9. ↑ Online 'Mendelian Inheritance in Man' (OMIM) 168461
  10. ↑ Online 'Mendelian Inheritance in Man' (OMIM) 133450
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