Kidney metastasis

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Kidney metastasis
Diagnosis in short

Metastatic adenocarcinoma involving the kidney. H&E stain.

Synonyms renal metastasis, metastatic disease involving the kidney

LM malignant neoplasm - morphology dependent on site of origin, often glandular
LM DDx urothelial carcinoma, primary adenocarcinoma of the renal pelvis, unclassified renal cell carcinoma
IHC PAX8 -ve (usually), vimentin -ve (usually)
Gross mass lesion - classically in cortex close to the glomerular vascular plexus
Site kidney

Clinical history +/-history malignancy
Symptoms +/-hematuria
Prevalence rare
Prognosis poor
Clin. DDx renal primary

Kidney metastasis, also renal metastasis, is a kidney tumour that arose elsewhere and spread to the kidney.

General

  • Rare.
  • History should be compelling.

Clinical:

  • +/-Hematuria seen in 12-31% of cases.[1]

Gross

  • Typically in cortex close to the glomerular vascular plexus.[2]

Microscopic

Features:

  • Malignant neoplasm - morphology dependent on site of origin and type.

Note:

DDx:

Images

Case

www

See also

References

  1. Bailey, JE.; Roubidoux, MA.; Dunnick, NR.. "Secondary renal neoplasms.". Abdom Imaging 23 (3): 266-74. PMID 9569294.
  2. 2.0 2.1 Cai, J.; Liang, G.; Cai, Z.; Yang, T.; Li, S.; Yang, J. (2013). "Isolated renal metastasis from squamous cell lung cancer.". Multidiscip Respir Med 8 (1): 2. doi:10.1186/2049-6958-8-2. PMID 23320514.
  3. Spires, SE.; Banks, ER.; Cibull, ML.; Munch, L.; Delworth, M.; Alexander, NJ. (Nov 1993). "Adenocarcinoma of renal pelvis.". Arch Pathol Lab Med 117 (11): 1156-60. PMID 8239939.