Interstitial cystitis

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Interstitial cystitis is a benign painful pathology of the urinary bladder.

It is also known as painful bladder syndrome.[1][2]

Hunner ulcer redirects here.[3]

General

  • Chronic cystitis, culture negative.

Epidemiology:[2]

  • Women > men.

Symptoms:[2]

  • Urgency.
  • Frequency.
  • Pain.

Treatment:

  • Difficult.[1]
  • Fulguration of ulcers (if present) may provide symptomatic relief.[3]

Gross

  • +/-Ulceration.

Microscopic

Features:[4]

  • +/-Ulceration (uncommon).

Note:

DDx:

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Urinary Bladder, Biopsy:
- Inflamed subepithelial tissue; NEGATIVE for appreciable amount of urothelium.
- NEGATIVE for evidence of malignancy.

Comment:
Deepers were cut (x4) and are non-contributory.

See also

References

  1. 1.0 1.1 Tanaka, T.; Nitta, Y.; Morimoto, K.; Nishikawa, N.; Nishihara, C.; Tamada, S.; Kawashima, H.; Nakatani, T. (2011). "Hyperbaric oxygen therapy for painful bladder syndrome/interstitial cystitis resistant to conventional treatments: long-term results of a case series in Japan.". BMC Urol 11: 11. doi:10.1186/1471-2490-11-11. PMID 21609485.
  2. 2.0 2.1 2.2 French, LM.; Bhambore, N. (May 2011). "Interstitial cystitis/painful bladder syndrome.". Am Fam Physician 83 (10): 1175-81. PMID 21568251.
  3. 3.0 3.1 Hillelsohn, JH.; Rais-Bahrami, S.; Friedlander, JI.; Okhunov, Z.; Kashan, M.; Rosen, L.; Moldwin, RM. (Dec 2012). "Fulguration for Hunner ulcers: long-term clinical outcomes.". J Urol 188 (6): 2238-41. doi:10.1016/j.juro.2012.08.013. PMID 23083651.
  4. Zhou, Ming; Magi-Galluzzi, Cristina (2006). Genitourinary Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 124. ISBN 978-0443066771.