Hidradenitis suppurativa

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Hidradenitis suppurativa (abbreviated HS), also known as acne inversa,[1] is a benign skin condition.

General

  • Uncommon - <1% of population.[2]
  • Onset usually after puberty and before 40 years old.[3]

May be associated with:[1]

Gross

Features:

  • Location - classically intertriginous areas.[4]
    • Axilla, buttocks, groin, inner thighs, breast (inframammary fold).

Microscopic

Features:[3]

  • Apocrine ducts plugged by keratin and dilated - key feature.
  • +/-Bacteria and inflammation in the congested ducts.
  • +/-Fibrosis (late).

DDx:

Images

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SKIN AND SUBCUTANEOUS TISSUE, RIGHT AXILLA, EXCISION:
- DILATED APOCRINE DUCTS AND A FIBROTIC DERMIS WITH MILD CHRONIC
  PERIVASCULAR INFLAMMATION, SEE COMMENT.
- EPIDERMAL INCLUSION CYSTS.

COMMENT:
The findings are compatible with hidradenitis suppurativa.

See also

References

  1. 1.0 1.1 Dessinioti C, Katsambas A, Antoniou C (2014). "Hidradenitis suppurrativa (acne inversa) as a systemic disease". Clin. Dermatol. 32 (3): 397–408. doi:10.1016/j.clindermatol.2013.11.006. PMID 24767187.
  2. McMillan K (May 2014). "Hidradenitis Suppurativa: Number of Diagnosed Patients, Demographic Characteristics, and Treatment Patterns in the United States". Am. J. Epidemiol.. doi:10.1093/aje/kwu078. PMID 24812161.
  3. 3.0 3.1 Radcliffe KW (February 1991). "Hidradenitis suppurativa". Genitourin Med 67 (1): 58. PMC 1194617. PMID 1916780. //www.ncbi.nlm.nih.gov/pmc/articles/PMC1194617/.
  4. Scheinfeld N (2013). "Hidradenitis suppurativa: A practical review of possible medical treatments based on over 350 hidradenitis patients". Dermatol. Online J. 19 (4): 1. PMID 24021361.