Hidradenitis suppurativa

Hidradenitis suppurativa (abbreviated HS), also known as acne inversa, is a benign skin condition.

General

• Uncommon - <1% of population.
• Onset usually after puberty and before 40 years old.

May be associated with:

• Crohn's disease.
• Obesity.

Gross

Features:

• Location - classically intertriginous areas.
  • Axilla, buttocks, groin, inner thighs, breast (inframammary fold).

Microscopic

Features:

• Apocrine ducts plugged by keratin and dilated - key feature.
• +/-Bacteria and inflammation in the congested ducts.
• +/-Fibrosis (late).

DDx:

• Pilonidal disease.

Images

• HS (scielo.br).

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SKIN AND SUBCUTANEOUS TISSUE, RIGHT AXILLA, EXCISION:
- DILATED APOCRINE DUCTS AND A FIBROTIC DERMIS WITH MILD CHRONIC
  PERIVASCULAR INFLAMMATION, SEE COMMENT.
- EPIDERMAL INCLUSION CYSTS.

COMMENT:
The findings are compatible with hidradenitis suppurativa.

See also

• Skin.