Haematopoiesis

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Haematopoiesis is the making of blood. Problems in haematopoiesis are numberous and the domain of hematology and hematopathology.

Normal haematopoiesis

Microscopic

One should see three cell lines:[1]

  • Erythroid cells.
  • Myeloid cells.
  • Megakaryocytes.

Images

www:

Extramedullary haematopoiesis

  • Abbreviated EMH.

General

  • In adults it is a compensatory mechanism for bone marrow dysfunction.

Cause:

Locations:[3]

Microscopic

Features:

  • Erythroid cells - esp. nucleated red blood cells.
  • Myeloid - granulocytes and granulocyte precursors.
  • Megakaryocytes - Large cells (50-100 μm) with abundant cytoplasm.
    • Make platelets.

Images

www:

See also

References

  1. URL: http://emedicine.medscape.com/article/199003-overview. Accessed on: 22 November 2010.
  2. URL: http://www.ouhsc.edu/histology/Text%20Sections/Hematopoiesis.html. Accessed on: 22 November 2010.
  3. URL: http://path.upmc.edu/cases/case283/dx.html. Accessed on: 14 January 2012.

External links