HELLP syndrome

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HELLP syndrome is an uncommon pathology of pregnancy that is diagnosed clinically and is defined by hemolysis, elevated liver enzymes and low platelets.


  • Diagnosed clinically.
  • Pathologically not the same as severe preclampsia.[1]


  • H = hemolysis.
  • EL = elevated liver enzymes.
  • LP = low platelets.



  • Thrombotic microangiopathic vasculopathy.
    • In essence: severe hypertrophic decidual vasculopathy. (???)

See also


  1. Vinnars MT, Wijnaendts LC, Westgren M, Bolte AC, Papadogiannakis N, Nasiell J (May 2008). "Severe preeclampsia with and without HELLP differ with regard to placental pathology". Hypertension 51 (5): 1295–9. doi:10.1161/HYPERTENSIONAHA.107.104844. PMID 18362224.
  2. Ornstein MH, Rand JH (July 1994). "An association between refractory HELLP syndrome and antiphospholipid antibodies during pregnancy; a report of 2 cases". J. Rheumatol. 21 (7): 1360–4. PMID 7966086.