Haematopoiesis
(Redirected from Extramedullary haematopoiesis)
Jump to navigation
Jump to search
Haematopoiesis is the making of blood. Problems in haematopoiesis are numberous and the domain of hematology and hematopathology.
Normal haematopoiesis
Microscopic
One should see three cell lines:[1]
- Erythroid cells.
- Myeloid cells.
- Megakaryocytes.
Images
- Extramedullary haematopoiesis - endometrial polyp - high mag.jpg
Nucleated RBCs - high mag. (WC)
www:
Extramedullary haematopoiesis
- Abbreviated EMH.
General
- In adults it is a compensatory mechanism for bone marrow dysfunction.
Cause:
- Any process that disrupts the bone marrow, e.g. fibrous dysplasia.
Locations:[3]
Microscopic
Features:
- Erythroid cells - esp. nucleated red blood cells.
- Myeloid - granulocytes and granulocyte precursors.
- Megakaryocytes - Large cells (50-100 μm) with abundant cytoplasm.
- Make platelets.
Images
- Nucleated red blood cells - endometrial polyp - high mag.jpg
Nucleated RBC - high mag. (WC)
www:
See also
References
- ↑ URL: http://emedicine.medscape.com/article/199003-overview. Accessed on: 22 November 2010.
- ↑ URL: http://www.ouhsc.edu/histology/Text%20Sections/Hematopoiesis.html. Accessed on: 22 November 2010.
- ↑ URL: http://path.upmc.edu/cases/case283/dx.html. Accessed on: 14 January 2012.