Dihydropyrimidine dehydrogenase deficiency

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Dihydropyrimidine dehydrogenase deficiency, abbreviated DPD, is an enzyme deficiency that is associated with toxicity to 5-fluorouracil (5-FU).[1]

See also

References

  1. Ezzeldin H, Diasio R (September 2004). "Dihydropyrimidine dehydrogenase deficiency, a pharmacogenetic syndrome associated with potentially life-threatening toxicity following 5-fluorouracil administration". Clin Colorectal Cancer 4 (3): 181–9. doi:10.3816/ccc.2004.n.018. PMID 15377401.