DNA sequence comparison
DNA sequence comparison is component of molecular pathology.
DNA sequencing redirect here.
This is still somewhat in flux.
FASTA: This contains just DNA sequence. The first line starts with '>' and contains the record name.
FASTQ: This contains DNA sequence data with quality scores: The quality scores are indicated by defined characters.
Basic local alignment search tool
- AKA BLAST.
- Go to BLAST web site ( http://blast.ncbi.nlm.nih.gov/Blast.cgi ).
- Enter sequence.
- Enter consensus sequence (can be found with OMIM).
- Hit enter.
- Ogino S, Gulley ML, den Dunnen JT, Wilson RB (February 2007). "Standard mutation nomenclature in molecular diagnostics: practical and educational challenges". J Mol Diagn 9 (1): 1–6. doi:10.2353/jmoldx.2007.060081. PMC 1867422. PMID 17251329. http://moldiag.highwire.org/cgi/content/full/9/1/1#B6.