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Immunostain in short

CD20 staining in a DLBCL.
Similar stains CD79a, PAX5
Use B-cell lymphomas
Subspeciality hematopathology
Normal staining pattern membranous
Positive most B-cell lymphomas

CD20 is a B-cell marker. It is positive in most B-cell lymphoma.


Negative B cell lymphomas

Abberant faint positive

  • T-cell lymphoma/leukemia - rare.[2]

See also


  1. Teruya-Feldstein, J.; Chiao, E.; Filippa, DA.; Lin, O.; Comenzo, R.; Coleman, M.; Portlock, C.; Noy, A. (Nov 2004). "CD20-negative large-cell lymphoma with plasmablastic features: a clinically heterogenous spectrum in both HIV-positive and -negative patients.". Ann Oncol 15 (11): 1673-9. doi:10.1093/annonc/mdh399. PMID 15520070.
  2. Kawano, R.; Niino, D.; Ohshima, K. (2016). "Six Cases of CD20-Positive Adult T-Cell Leukemia.". J Clin Exp Hematop 56 (2): 119-125. doi:10.3960/jslrt.56.119. PMID 27980301.