Colitis cystica profunda

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Colitis cystica profunda
Diagnosis in short

LM mucin filled cysts in submucosa or deeper
LM DDx well-differentiated colorectal adenocarcinoma, mucinous adenocarcinoma
Site colon and rectum, usu. distal

Associated Dx cap polyposis
Prevalence very rare (case reports)
Endoscopy polypoid lesion(s)
Prognosis good, benign
Clin. DDx other polypoid lesions

Colitis cystica profunda, abbreviated CCP, a very rare gastrointestinal pathology.






  • Mucin filled cysts in the submucosa[2][5] or deeper.[6]
  • +/-Inflammation.



See also


  1. 1.0 1.1 Dolar, E.; Kiyici, M.; Yilmazlar, T.; Gürel, S.; Nak, SG.; Gülten, M. (Sep 2007). "Colitis cystica profunda.". Turk J Gastroenterol 18 (3): 206-7. PMID 17891698.
  2. 2.0 2.1 2.2 Kayaçetin, E.; Kayaçetin, S.. "Colitis cystica profunda simulating rectal carcinoma.". Acta Chir Belg 105 (3): 306-8. PMID 16018526.
  3. Mitsunaga, M.; Izumi, M.; Uchiyama, T.; Sawabe, A.; Tanida, E.; Hosono, K.; Abe, T.; Shirahama, K. et al. (Mar 2009). "Colonic adenocarcinoma associated with colitis cystica profunda.". Gastrointest Endosc 69 (3 Pt 2): 759-60; discussion 760-1. doi:10.1016/j.gie.2008.12.240. PMID 19251024.
  4. Arana, R.; Fléjou, JF.; Parc, Y.; El-Murr, N.; Cosnes, J.; Svrcek, M. (Sep 2013). "Cap polyposis and colitis cystica profunda: a rare association.". Histopathology. doi:10.1111/his.12292. PMID 24118052.
  5. 5.0 5.1 Higuera Alvarez, R.; García, Jde L.; San Miguel, G.; Castro, B. (Apr 2008). "[Colitis cystica profunda].". Rev Esp Enferm Dig 100 (4): 240-2. PMID 18563984.
  6. Cite error: Invalid <ref> tag; no text was provided for refs named pmid21212765