Mammary hamartoma

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Mammary hamartoma, also breast hamartoma, is an uncommon benign pathology of the breast.

General

Gross

  • Well-circumscribed - key feature.

Microscopic

Features:[1]

  • Disordered arrangement of ductal and lobular structures.
  • Normal arrangement of cells with in the ductal structures, i.e. myoepithelium and epithelium present.
  • Variable features:[2]
    1. Adipose tissue - predominant.
    2. Dense fibrosis tissue - predominant.
    3. Cystic glandular dilation.

Notes:

  • If adipose tissue predominates; it may be labeled adenolipoma.[2]

DDx:

Images

IHC

  • None - it's a H&E diagnosis.

See also

References

  1. O'Malley, Frances P.; Pinder, Sarah E. (2006). Breast Pathology: A Volume in Foundations in Diagnostic Pathology series (1st ed.). Churchill Livingstone. pp. 117. ISBN 978-0443066801.
  2. 2.0 2.1 URL: http://surgpathcriteria.stanford.edu/breast/mammhamart/. Accessed on: 4 October 2011.
  3. Tse, GM.; Law, BK.; Ma, TK.; Chan, AB.; Pang, LM.; Chu, WC.; Cheung, HS. (Dec 2002). "Hamartoma of the breast: a clinicopathological review.". J Clin Pathol 55 (12): 951-4. PMC 1769817. PMID 12461066. //www.ncbi.nlm.nih.gov/pmc/articles/PMC1769817/.