Azzopardi phenomenon

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Azzopardi phenomenon, also Azzopardi effect, is something one occasionally sees as a pathologist -- in small cell carcinoma.


  • Smudged DNA.[1]
    • Looks like smudged ink -- from a crappy ball-point pen.



  • Named after the pathologist (Azzopardi) that showed it isn't calcium.[1][2]

See also


  1. 1.0 1.1 Pritt BS, Cooper K (September 2003). "The Azzopardi phenomenon". Arch. Pathol. Lab. Med. 127 (9): 1231. PMID 12951999.
  2. AZZOPARDI, JG. (Oct 1959). "Oat-cell carcinoma of the bronchus.". J Pathol Bacteriol 78: 513-9. PMID 13795444.