From Libre Pathology
|Diagnosis in short|
Compatible with angiodysplasia. H&E stain.
|LM||dilated vessels in mucosa and submucosa|
|LM DDx||prominent vessels|
|Clinical history||older individuals|
|Signs||bleeding from rectum|
|Endoscopy||red lesion - typically right colon or cecum|
|Clin. DDx||Other causes of lower GI bleed|
Angiodysplasia is a benign pathology of the large bowel.
- Clinical diagnosis.
- Cause of (lower) GI haemorrhage.
- Generally, not a problem pathologists see.
- May be associated with aortic stenosis; known as Heyde syndrome.
- Older people.
- Thought to be caused by the higher wall tension of cecum (due to larger diameter) and result from (intermittent) venous occlusion/focal dilation of vessels.
- Cecum - classic location.
- Dilated blood vessels in the mucosa and submucosa.
- Crohn's disease - may be associated increase vascularity.
- Hui YT, Lam WM, Fong NM, Yuen PK, Lam JT (August 2009). "Heyde's syndrome: diagnosis and management by the novel single-balloon enteroscopy". Hong Kong Med J 15 (4): 301–3. PMID 19652242. http://www.hkmj.org/abstracts/v15n4/301.htm.
- Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease (7th ed.). St. Louis, Mo: Elsevier Saunders. pp. 854. ISBN 0-7216-0187-1.
- Hemingway, AP. (Apr 1988). "Angiodysplasia: current concepts.". Postgrad Med J 64 (750): 259-63. PMID 3054852.