Amyloid in the seminal vesicles
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Seminal vesicle with amyloid. H&E stain.
Amyloid in the seminal vesicles is a relatively common histologic finding.
General
Significance/management
- A paper by Yang et al. (looking at a small series) suggests seminal vesicle amyloid is not necessary to work-up further.[3]
Note:
- Amyloid in the prostate is rare and should be worked-up.[4]
Microscopic
Features:
- Hyaline material with a "cracked" appearance surrounding the glandular component of the seminal vesicles.
Images
SV with amyloid - very low mag.
SV with amyloid - low mag.
SV with amyloid - intermed. mag.
SV with amyloid - high mag.
SV with amyloid - very high mag.
Stains
- Congo red +ve.
Images
SV with amyloid - congo red - low mag.
SV with amyloid - congo red - intermed. mag.
See also
References
- ↑ Argon, A.; Sımşır, A.; Sarsik, B.; Tuna, B.; Yörükoğlu, K.; Nıflıoğlu, GG.; Sen, S. (2012). "Amyloidosis of seminal vesicles; incidence and pathologic characteristics.". Turk Patoloji Derg 28 (1): 44-8. doi:10.5146/tjpath.2012.01096. PMID 22207431.
- ↑ Pitkänen, P.; Westermark, P.; Cornwell, GG.; Murdoch, W. (Jan 1983). "Amyloid of the seminal vesicles. A distinctive and common localized form of senile amyloidosis.". Am J Pathol 110 (1): 64-9. PMID 6849372.
- ↑ Yang, Z.; Laird, A.; Monaghan, A.; Seywright, M.; Ahmad, I.; Leung, HY. (Jan 2013). "Incidental seminal vesicle amyloidosis observed in diagnostic prostate biopsies--are routine investigations for systemic amyloidosis warranted?". Asian J Androl 15 (1): 149-51. doi:10.1038/aja.2012.125. PMID 23223033.
- ↑ Nevo A, Muchtar E, Stern KL, Moore JP, Cheney SM, Humphreys MR, Grogan M, Stanton ML (November 2020). "The Clinical Implication of Incidental Prostatic Amyloidosis". Urology 145: 253–257. doi:10.1016/j.urology.2020.08.053. PMID 32961226.