Lateral aberrant thyroid tissue

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Lateral aberrant thyroid tissue is thyroid tissue lateral to the jugular vein, that is not within a lymph node.

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General

  • Lateral aberrant thyroid tissue is considered metastatic thyroid carcinoma (papillary thyroid carcinoma) even if it looks benign;[1] however, this dictum is disputed.[2]
  • Morphologically benign thyroid tissue in a lymph node appears to have a benign behaviour, if found incidentally.[3]

Notes:

  • The level VI and VII lymph nodes are medial to the jugular.

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Comment

Morphologically benign appearing thyroid tissue (TTF-1 POSITIVE, thyroglobin POSITIVE, calcitonin NEGATIVE) was found in a lymph node. Correlation with additional testing is suggested to exclude the possibility of significant thyroid pathology.

See also

References

  1. Johnson, RW.; Saha, NC. (Jun 1962). "The so-called lateral aberrant thyroid.". Br Med J 1 (5293): 1668-9. PMC 1958877. PMID 14452106. //www.ncbi.nlm.nih.gov/pmc/articles/PMC1958877/.
  2. Escofet, X.; Khan, AZ.; Mazarani, W.; Woods, WG. (Jan 2007). "Lessons to be learned: a case study approach. Lateral aberrant thyroid tissue: is it always malignant?". J R Soc Promot Health 127 (1): 45-6. PMID 17319317.
  3. León, X.; Sancho, FJ.; García, J.; Sañudo, JR.; Orús, C.; Quer, M. (Mar 2005). "Incidence and significance of clinically unsuspected thyroid tissue in lymph nodes found during neck dissection in head and neck carcinoma patients.". Laryngoscope 115 (3): 470-4. doi:10.1097/01.mlg.0000157841.63283.87. PMID 15744160.