Zenker's diverticulum

From Libre Pathology
Revision as of 15:55, 9 November 2015 by Michael (talk | contribs) (→‎General)
Jump to navigation Jump to search

Zenker's diverticulum is an outpouching of the mucosa and submucosa at the junction of the pharynx and esophagus.

It is also known as cricopharyngeal diverticulum, pharyngoesophageal diverticulum and hypopharyngeal diverticulum.[1]

General

Clinical:[5]

  • Eldery.
  • Dysphagia.
  • May mimic a thyroid nodule.[7]
  • +/-Aspiration of food.

Gross

Images

Microscopic

Features:[7]

DDx:

Sign out

Submitted as "Zenker's Diverticulum", Excision:
- Squamous mucosa with parakeratosis, mild chronic inflammation 
  and fibrosis; compatible with Zenker's diverticulum.
- NEGATIVE for dysplasia and NEGATIVE for malignancy. 

Alternate

Submitted as "Zenker's Diverticulum", Excision:
- Squamous mucosa with mild chronic inflammation and reactive 
  changes; compatible with Zenker's diverticulum.
- Benign skeletal muscle.
- NEGATIVE for dysplasia and NEGATIVE for malignancy. 

See also

References

  1. Nuño-Guzmán, CM.; García-Carrasco, D.; Haro, M.; Arróniz-Jáuregui, J.; Corona, JL.; Salcido, M.. "Zenker's Diverticulum: Diagnostic Approach and Surgical Management.". Case Rep Gastroenterol 8 (3): 346-52. doi:10.1159/000369130. PMID 25759630.
  2. Acar, T.; Savaş, R.; Kocaçelebi, K.; Ersöz, G. (Sep 2015). "Squamous cell carcinoma arising from a Zenker's diverticulum: contribution of FDG-PET/CT to the diagnosis.". Dis Esophagus. doi:10.1111/dote.12406. PMID 26415863.
  3. Wakita, A.; Motoyama, S.; Sato, Y.; Yoshino, K.; Sasaki, T.; Saito, H.; Minamiya, Y.; Ogawa, J. (2012). "Squamous cell carcinoma in an esophageal diverticulum below the aortic arch.". Int J Surg Case Rep 3 (11): 574-6. doi:10.1016/j.ijscr.2012.07.010. PMID 22940699.
  4. Iacobuzio-Donahue, Christine A.; Montgomery, Elizabeth A. (2005). Gastrointestinal and Liver Pathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 7. ISBN 978-0443066573.
  5. 5.0 5.1 Law, R.; Katzka, DA.; Baron, TH. (Nov 2014). "Zenker's Diverticulum.". Clin Gastroenterol Hepatol 12 (11): 1773-82; quiz e111-2. doi:10.1016/j.cgh.2013.09.016. PMID 24055983.
  6. Iacobuzio-Donahue, Christine A.; Montgomery, Elizabeth A. (2005). Gastrointestinal and Liver Pathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 6. ISBN 978-0443066573.
  7. 7.0 7.1 Singaporewalla, RM.; Mukherjee, JJ.; Thamboo, TP.; Cheah, WK. (Dec 2011). "Pharyngoesophageal diverticulum resembling a thyroid nodule on ultrasound.". Head Neck 33 (12): 1800-3. doi:10.1002/hed.21474. PMID 20665743.