98
edits
Difference between revisions of "Wilms tumour"
Jump to navigation
Jump to search
→General
(→Gross) |
|||
| (2 intermediate revisions by the same user not shown) | |||
| Line 34: | Line 34: | ||
==General== | ==General== | ||
*Common abdominal [[pediatric pathology|pediatric]] tumour. | *Common abdominal [[pediatric pathology|pediatric]] tumour. | ||
**Affects approximately 1 in 8000 children. | |||
**There is no sex predilection and the mean patient age at diagnosis ranges among 37 to 43 months. | |||
*May be associated with a syndrome:<ref>URL: [http://emedicine.medscape.com/article/989398-overview http://emedicine.medscape.com/article/989398-overview]. Accessed on: 9 March 2011.</ref> | *May be associated with a syndrome:<ref>URL: [http://emedicine.medscape.com/article/989398-overview http://emedicine.medscape.com/article/989398-overview]. Accessed on: 9 March 2011.</ref> | ||
**WAGR syndrome (Wilms tumour, Aniridia (absence of iris), GU abnormalities, Retardation).<ref>{{OMIM|194072}}</ref> | **WAGR syndrome (Wilms tumour, Aniridia (absence of iris), GU abnormalities, Retardation).<ref>{{OMIM|194072}}</ref> | ||
| Line 40: | Line 42: | ||
==Gross== | ==Gross== | ||
Features <ref name="pmid10193955">{{ | Features <ref name="pmid10193955">{{Cite journal | last1 = Coppes | first1 = MJ. | last2 = Arnold | first2 = M. | last3 = Beckwith | first3 = JB. | last4 = Ritchey | first4 = ML. | last5 = D'Angio | first5 = GJ. | last6 = Green | first6 = DM. | last7 = Breslow | first7 = NE. | title = Factors affecting the risk of contralateral Wilms tumor development: a report from the National Wilms Tumor Study Group. | journal = Cancer | volume = 85 | issue = 7 | pages = 1616-25 | month = Apr | year = 1999 | doi = | PMID = 10193955 }}</ref> | ||
*Most nephroblastomas are unifocal. | *Most nephroblastomas are unifocal. | ||
**Usually solitary, rounded, multilobular masses sharply demarcated from adjacent parenchyma. | **Usually solitary, rounded, multilobular masses sharply demarcated from adjacent parenchyma. | ||