Vocal cord

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Vocal cord, also vocal fold, are the structures that make sound.

Pathology of the vocal cords:[1]

Reinke's edema

General

  • Associated with smoking and alcohol.[2][3]
  • Typical presentation: dysphonia.[4]
  • May have DNA copy number variations - but no clearly established link to cancer.[5]

Gross

Features:[4]

  • Polypoid enlargement of vocal cords (unilateral or bilateral).


References

  1. Saraniti C, Patti G, Verro B (April 2023). "Sulcus Vocalis and Benign Vocal Cord Lesions: Is There Any Relationship?". Int J Environ Res Public Health 20 (9). doi:10.3390/ijerph20095654. PMC 10177882. PMID 37174173. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177882/.
  2. Cheah SC, Yee LW, Kok WL, Nazri Zamri FI, Baki MM (September 2023). "A Rare Cause of Acute Dyspnoea: Reinke Oedema". Indian J Otolaryngol Head Neck Surg 75 (3): 2420–2422. doi:10.1007/s12070-023-03714-4. PMID 37636736.
  3. Sato K, Kurita T, Sato F, Sato K, Chitose SI, Ono T, Umeno H (September 2023). "Pathogenesis of Reinke's Edema of the Vocal Fold". Laryngoscope. doi:10.1002/lary.31084. PMID 37772971.
  4. 4.0 4.1 Tavaluc R, Tan-Geller M (August 2019). "Reinke's Edema". Otolaryngol Clin North Am 52 (4): 627–635. doi:10.1016/j.otc.2019.03.006. PMID 31101355.
  5. Móz LE, Martins RH, Lapa RM, Villacis RA, Dos Reis PP, Rogatto SR (2023). "DNA rare copy number alterations in Reinke's Edema". Braz J Otorhinolaryngol 89 (2): 279–284. doi:10.1016/j.bjorl.2022.09.002. PMC 10071534. PMID 36243603. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071534/.