Difference between revisions of "Villous hypoplasia"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Distal villous hypoplasia -- low mag.jpg | |||
| Width = | |||
| Caption = Distal villous hypoplasia. [[H&E stain]]. | |||
| Synonyms = terminal villus deficiency, distal villous hypoplasia | |||
| Micro = small & round villi (30-60 micrometers), "long" villi (due to lack of branching), absence of syncytial knots, wide intervillous space | |||
| Subtypes = | |||
| LMDDx = | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = usu. small placenta | |||
| Grossing = | |||
| Site = [[placenta]] | |||
| Assdx = [[IUGR]], [[small placenta]] | |||
| Syndromes = | |||
| Clinicalhx = small fetus | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = not common | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Villous hypoplasia''', also '''distal villous hypoplasia''', is pathology of the [[placenta]] associated with [[intrauterine growth restriction]]. | |||
It is also known as '''terminal villus deficiency'''.<ref name=Ref_Placenta346>{{Ref Placenta|346}}</ref> | |||
==General== | |||
*Associated with [[IUGR]].<ref name=Ref_Placenta346>{{Ref Placenta|346}}</ref><ref name=fitzgerald>{{Cite journal | last1 = Fitzgerald | first1 = B. | last2 = Kingdom | first2 = J. | last3 = Keating | first3 = S. | title = Distal villous hypoplasia. | journal = Diagnostic Histopathology | volume = 18 | issue = 5 | pages = 195-200 | month = May | year = 2012 | doi = 10.1016/j.mpdhp.2012.02.005 | PMID = }}</ref> | |||
*Atypical Doppler flow measurements: high Doppler resistance index.<ref name=Ref_Placenta346>{{Ref Placenta|346}}</ref> | |||
==Microscopic== | |||
Features:<ref name=Ref_Placenta346>{{Ref Placenta|346}}</ref> | |||
*Small, round villi (30-60 micrometers). | |||
*"Long" villi (due to lack of branching). | |||
*Absence of syncytial knots. | |||
*Wide intervillous space. | |||
===Images=== | |||
<gallery> | |||
Image: Distal villous hypoplasia - alt -- very low mag.jpg | DVH - very low mag. | |||
Image: Distal villous hypoplasia - alt -- low mag.jpg | DVH - low mag. | |||
Image: Distal villous hypoplasia - alt -- intermed mag.jpg | DVH - intermed. mag. | |||
Image: Distal villous hypoplasia -- low mag.jpg | DVH - low mag. | |||
Image: Distal villous hypoplasia -- intermed mag.jpg | DVH - intermed. mag. | |||
Image: Distal villous hypoplasia -- high mag.jpg | DVH - high mag. | |||
Image: Distal villous hypoplasia -- very high mag.jpg | DVH - very high mag. | |||
</gallery> | |||
==Sign out== | |||
<pre> | |||
PLACENTA AND MEMBRANES, BIRTH: | |||
- SMALL PLACENTA FOR GESTATIONAL AGE (265 GRAMS - TRIMMED , POST FIXATION). | |||
- FETAL MEMBRANES WITHIN NORMAL LIMITS. | |||
- THREE-VESSEL CORD WITHIN NORMAL LIMITS. | |||
- PLACENTAL DISC WITH VILLOUS HYPOPLASIA. | |||
COMMENT: | |||
THE PLACENTAL FINDINGS ARE COMPATIBLE WITH INTRAUTERINE GROWTH RESTRICTION. | |||
</pre> | |||
==See also== | |||
*[[Placenta]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Placenta]] | |||
Latest revision as of 04:54, 31 January 2015
| Villous hypoplasia | |
|---|---|
| Diagnosis in short | |
 Distal villous hypoplasia. H&E stain. | |
|
| |
| Synonyms | terminal villus deficiency, distal villous hypoplasia |
|
| |
| LM | small & round villi (30-60 micrometers), "long" villi (due to lack of branching), absence of syncytial knots, wide intervillous space |
| Gross | usu. small placenta |
| Site | placenta |
|
| |
| Associated Dx | IUGR, small placenta |
| Clinical history | small fetus |
| Prevalence | not common |
Villous hypoplasia, also distal villous hypoplasia, is pathology of the placenta associated with intrauterine growth restriction.
It is also known as terminal villus deficiency.[1]
General
Microscopic
Features:[1]
- Small, round villi (30-60 micrometers).
- "Long" villi (due to lack of branching).
- Absence of syncytial knots.
- Wide intervillous space.
Images
DVH - very low mag.
DVH - low mag.
DVH - intermed. mag.
DVH - low mag.
DVH - intermed. mag.
DVH - high mag.
DVH - very high mag.
Sign out
PLACENTA AND MEMBRANES, BIRTH: - SMALL PLACENTA FOR GESTATIONAL AGE (265 GRAMS - TRIMMED , POST FIXATION). - FETAL MEMBRANES WITHIN NORMAL LIMITS. - THREE-VESSEL CORD WITHIN NORMAL LIMITS. - PLACENTAL DISC WITH VILLOUS HYPOPLASIA. COMMENT: THE PLACENTAL FINDINGS ARE COMPATIBLE WITH INTRAUTERINE GROWTH RESTRICTION.
See also
References
- ↑ 1.0 1.1 1.2 1.3 Baergen, Rebecca N. (2011). Manual of Pathology of the Human Placenta (2nd ed.). Springer. pp. 346. ISBN 978-1441974938.
- ↑ Fitzgerald, B.; Kingdom, J.; Keating, S. (May 2012). "Distal villous hypoplasia.". Diagnostic Histopathology 18 (5): 195-200. doi:10.1016/j.mpdhp.2012.02.005.