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Difference between revisions of "Urothelial carcinoma-like prostatic carcinoma"
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Urothelial carcinoma-like prostatic carcinoma (view source)
Revision as of 06:14, 20 April 2016
, 06:14, 20 April 2016→General
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'''Urothelial carcinoma-like prostatic carcinoma''' is a [[prostatic carcinoma]] that histologically mimics [[urothelial carcinoma]]. | '''Urothelial carcinoma-like prostatic carcinoma''', abbreviated '''UCLPC''', is a [[prostatic carcinoma]] that histologically mimics [[urothelial carcinoma]]. | ||
It is not a formally recognized type of [[prostate cancer]]. | It is not a formally recognized type of [[prostate cancer]]. | ||
''Prostatic carcinoma with pseudopapillae'' and ''prostatic adenocarcinoma with pseudopapillae'' redirect here. | |||
==General== | ==General== | ||
* | *Histologic features of high grade urothelial carcinomas and high grade prostatic carcinomas overlap. | ||
*Relative proximity of the [[urinary bladder]] and [[prostate]] results in clinical scenarios where the primary site is not readily apparent. | |||
Clinical: | |||
*History of urothelial carcinoma lacking. | |||
*+/-Elevated [[PSA]]. | |||
==Gross== | |||
Classic tumour locations: | |||
*Bladder neck. | |||
*Trigone/base of bladder. | |||
*Prostatic [[urethra]]. | |||
==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Large epithelioid cells with prominent nucleoli. | *Large epithelioid cells with [[prominent nucleoli]] and (usually) moderate [[nuclear pleomorphism]]. | ||
*+/-Papillary structures (pseudopapillae).<ref name=pmid24503758/> | *+/-Papillary structures (pseudopapillae).<ref name=pmid24503758/> | ||
*+/-Features suggestive of prostatic carcinoma - cribriforming glands ''or'' poorly formed glandular structures. | *+/-Features suggestive of prostatic carcinoma - cribriforming glands ''or'' poorly formed glandular structures. | ||
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[[Category:Genitourinary pathology]] | [[Category:Genitourinary pathology]] | ||
[[Category:Prostate carcinoma]] | |||