Difference between revisions of "Tumour suppressor gene"

Revision as of 06:10, 16 December 2014

A tumour suppressor gene is a gene that acts to protect the organism which it is within from developing cancer.

Tumour suppressors:

Gene	Syndrome or disease
TP53 (p53)^[1]	Li-Fraumeni syndrome
BRCA1^[2]	Familial breast-ovarian cancer 1
RB1^[3]
VHL^[4]	Von Hippel-Lindau disease
NF1^[5]	Neurofibromatosis type 1

@@ Line 1: / Line 1: @@
 A '''tumour suppressor gene''' is a gene that acts to protect the organism which it is within from developing [[cancer]].
-Examples of tumour suppressors:
+==Examples==
-*TP53 (p53).<ref>{{OMIM|191170}}</ref>
+Tumour suppressors:
-*[[BRCA1]].<ref>{{OMIM|113705}}</ref>
+{| class="wikitable sortable"
-*RB1.<ref>{{OMIM|614041}}</ref>
+! Gene
-*VHL.<ref>{{OMIM|608537}}</ref>
+! Syndrome or disease
-*NF1.<ref>{{OMIM|613113}}</ref>
+|-
+| TP53 (p53)<ref>{{OMIM|191170}}</ref>
+| [[Li-Fraumeni syndrome]]
+|-
+| [[BRCA1]]<ref>{{OMIM|113705}}</ref>
+| Familial breast-ovarian cancer 1
+|-
+| RB1<ref>{{OMIM|614041}}</ref>
+|
+|-
+| VHL<ref>{{OMIM|608537}}</ref>
+| [[Von Hippel-Lindau disease]]
+|-
+| NF1<ref>{{OMIM|613113}}</ref>
+| [[Neurofibromatosis type 1]]
+|}
 ==See also==