Tularemia
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Tularemia is an infectious disease that cause lymphadenopathy.
General
- Caused by Francisella tularensis, a Gram-negative coccobacillus.[1]
- Rare.
Treatment:
- Antibiotics.
Gross
- Lymphadenopathy.
- Typically axillary or cervical (like cat scratch disease).[2]
Microscopic
Features:
- Necrotizing granulomas with:
- Neutrophils present in microabscess (necrotic debris) - key feature.
- Microabscesses often described as "stellate" (star-shaped).
- Neutrophils present in microabscess (necrotic debris) - key feature.
- Microorganisms consistent with F. tularensis.
DDx of stellate abscess in lymph nodes - cat split:[3]
- Cat-scratch disease.
- Sporotrichosis.
- Lymphogranuloma venereum.
- Tularemia.
See also
References
- ↑ Dentan, C.; Pavese, P.; Pelloux, I.; Boisset, S.; Brion, JP.; Stahl, JP.; Maurin, M. (Jun 2013). "Treatment of tularemia in pregnant woman, France.". Emerg Infect Dis 19 (6): 996-8. doi:10.3201/eid1906.130138. PMID 23735285.
- ↑ Asano, S. (2012). "Granulomatous lymphadenitis.". J Clin Exp Hematop 52 (1): 1-16. PMID 22706525.
- ↑ URL: http://www.dermpathmd.com/mnemonics/mnemonics_dermatopathology.htm. Accessed on: 23 September 2011.