Difference between revisions of "Trichilemmoma"

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#redirect [[Dermatologic_neoplasms#Trichilemmoma]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = SkinTumors-P6190341.JPG
| Width      =
| Caption    = Trichilemmoma. [[H&E stain]].
| Synonyms  =
| Micro      = superficial dermal lesion contiguous with the epidermis; core of lesion has cuboidal cells with round nuclei, eosinophilic-clear cytoplasm; periphery of lesion surrounded by hyaline band, has peripheral palisading
| Subtypes  =
| LMDDx      = [[trichilemmal carcinoma]], [[basal cell carcinoma]], [[inverted follicular keratosis]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = [[skin]]
| Assdx      =
| Syndromes  = [[Cowden syndrome]]
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = uncommon
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    =
| Tx        =
}}
'''Trichilemmoma''' is an uncommon [[Dermatologic neoplasms|skin tumour]].
 
==General==
*Benign neoplasm with features of the pilosebaceous follicular epithelium.<ref>URL: [http://emedicine.medscape.com/article/1059940-overview http://emedicine.medscape.com/article/1059940-overview]. Accessed on: 2 September 2011.</ref>
*Associated with ''[[nevus sebaceous]]''.<ref name=pmid16503928>{{Cite journal  | last1 = Baykal | first1 = C. | last2 = Buyukbabani | first2 = N. | last3 = Yazganoglu | first3 = KD. | last4 = Saglik | first4 = E. | title = [Tumors associated with nevus sebaceous]. | journal = J Dtsch Dermatol Ges | volume = 4 | issue = 1 | pages = 28-31 | month = Jan | year = 2006 | doi = 10.1111/j.1610-0387.2006.05855.x | PMID = 16503928 }}</ref>
*Muliple trichilemmomas associated with [[Cowden syndrome]].<ref name=Ref_Derm386>{{Ref Derm|386}}</ref>
 
==Microscopic==
Features:<ref name=Ref_Derm386>{{Ref Derm|386}}</ref>
*Superficial dermal lesion contiguous with the epidermis:
**Core of lesion:
***Cuboidal cells with round nuclei, eosinophilic-clear cytoplasm.
**Periphery of lesion:
***Surrounded by hyaline band.
***Peripheral palisading.
 
DDx:
*[[Trichilemmal carcinoma]].
*[[Basal cell carcinoma]].
*[[Inverted follicular keratosis]].
 
===Images===
*[http://dermimages.med.jhmi.edu/images/trichilemmoma_1_060109.jpg Trichilemmoma (jhmi.edu)].<ref>URL: [http://dermatlas.med.jhmi.edu/derm/indexDisplay.cfm?ImageID=667496720 http://dermatlas.med.jhmi.edu/derm/indexDisplay.cfm?ImageID=667496720]. Accessed on: 2 September 2011.</ref>
*[http://www.flickr.com/photos/40981620@N04/3812019838/in/pool-1185084@N23/ Trichilemmoma - low mag. (flickr.com/Irlam)].
*[http://www.flickr.com/photos/40981620@N04/3812019930/in/pool-1185084@N23/ Trichilemmoma - intermed. mag. (flickr.com/Irlam)].
*[http://www.flickr.com/photos/40981620@N04/3811204517/in/pool-1185084@N23/ Trichilemmoma - high mag. (flickr.com/Irlam)].
 
==See also==
*[[Dermatologic neoplasms]].
*[[Cowden syndrome]].
 
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Dermatologic neoplasms]]

Latest revision as of 03:37, 20 February 2019

Trichilemmoma
Diagnosis in short

Trichilemmoma. H&E stain.

LM superficial dermal lesion contiguous with the epidermis; core of lesion has cuboidal cells with round nuclei, eosinophilic-clear cytoplasm; periphery of lesion surrounded by hyaline band, has peripheral palisading
LM DDx trichilemmal carcinoma, basal cell carcinoma, inverted follicular keratosis
Site skin

Syndromes Cowden syndrome

Prevalence uncommon
Prognosis benign

Trichilemmoma is an uncommon skin tumour.

General

Microscopic

Features:[3]

  • Superficial dermal lesion contiguous with the epidermis:
    • Core of lesion:
      • Cuboidal cells with round nuclei, eosinophilic-clear cytoplasm.
    • Periphery of lesion:
      • Surrounded by hyaline band.
      • Peripheral palisading.

DDx:

Images

See also

References

  1. URL: http://emedicine.medscape.com/article/1059940-overview. Accessed on: 2 September 2011.
  2. Baykal, C.; Buyukbabani, N.; Yazganoglu, KD.; Saglik, E. (Jan 2006). "[Tumors associated with nevus sebaceous].". J Dtsch Dermatol Ges 4 (1): 28-31. doi:10.1111/j.1610-0387.2006.05855.x. PMID 16503928.
  3. 3.0 3.1 Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 386. ISBN 978-0443066542.
  4. URL: http://dermatlas.med.jhmi.edu/derm/indexDisplay.cfm?ImageID=667496720. Accessed on: 2 September 2011.