Difference between revisions of "Thyroid cytopathology"

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*Granular chromatin.
*Granular chromatin.
*Cytoplasm - often not distinct.
*Cytoplasm - often not distinct.
*Scattered naked nuclei.<ref name=pmid24255635>{{Cite journal  | last1 = Heo | first1 = I. | last2 = Park | first2 = S. | last3 = Jung | first3 = CW. | last4 = Koh | first4 = JS. | last5 = Lee | first5 = SS. | last6 = Seol | first6 = H. | last7 = Choi | first7 = HS. | last8 = Cho | first8 = SY. | title = Fine needle aspiration cytology of parathyroid lesions. | journal = Korean J Pathol | volume = 47 | issue = 5 | pages = 466-71 | month = Oct | year = 2013 | doi = 10.4132/KoreanJPathol.2013.47.5.466 | PMID = 24255635 }}</ref>
*+/-Nuclear moulding.
*+/-Nuclear moulding.
*+/-Nuclear overlap.
*+/-Nuclear overlap.
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Images:
Images:
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770637/figure/f1/ Parathyroid gland (nih.gov)].<ref name=pmid15790694>{{Cite journal  | last1 = Johnson | first1 = SJ. | last2 = Sheffield | first2 = EA. | last3 = McNicol | first3 = AM. | title = Best practice no 183. Examination of parathyroid gland specimens. | journal = J Clin Pathol | volume = 58 | issue = 4 | pages = 338-42 | month = Apr | year = 2005 | doi = 10.1136/jcp.2002.002550 | PMID = 15790694 | PMC = 1770637 }}</ref>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770637/figure/f1/ Parathyroid gland (nih.gov)].<ref name=pmid15790694>{{Cite journal  | last1 = Johnson | first1 = SJ. | last2 = Sheffield | first2 = EA. | last3 = McNicol | first3 = AM. | title = Best practice no 183. Examination of parathyroid gland specimens. | journal = J Clin Pathol | volume = 58 | issue = 4 | pages = 338-42 | month = Apr | year = 2005 | doi = 10.1136/jcp.2002.002550 | PMID = 15790694 | PMC = 1770637 }}</ref>
DDx of naked nuclei:
*[[Granular cell tumour]].
*Parathyroid.<ref name=pmid19283690/>


=Adequacy criteria=
=Adequacy criteria=
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   material. Scant follicular cells, Hurthle cells and colloid present in a background of  
   material. Scant follicular cells, Hurthle cells and colloid present in a background of  
   mixed inflammatory cells and abundant macrophages.   
   mixed inflammatory cells and abundant macrophages.   
Note: A repeat aspiration should be considered if clinically warranted.
</pre>
====Alternate====
<pre>
Thyroid Gland, Right Lobe, Fine Needle Aspiration:
- Non-diagnostic. (Category I)
Specimen processed and examined, but unsatisfactory due to scant cellularity. 
Some cellular degeneration noted, rare colloid and inflammatory cells present.


Note: A repeat aspiration should be considered if clinically warranted.  
Note: A repeat aspiration should be considered if clinically warranted.  
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**Multinucleation.
**Multinucleation.


Diagnosis by MB:
DDx:
*If single cells -- need abundant.
*[[Granular cell tumour]].


====Images====
====Images====
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DDx:
DDx:
*Anaplastic carcinoma.
*[[anaplastic thyroid carcinoma|Anaplastic carcinoma]].


Images:
Images:
48,436

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