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Difference between revisions of "Testis"
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replace GUP refs
m (→General) |
m (replace GUP refs) |
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| Intratubular germ cell neoplasia (ITGCN) | | Intratubular germ cell neoplasia (ITGCN) | ||
| nests of small fried egg cells | | nests of small fried egg cells | ||
| large central nucleus, clear <br>cytoplasm, squared-off nuclear membrane, nucleoli<ref>GUP | | large central nucleus, clear <br>cytoplasm, squared-off nuclear membrane, nucleoli<ref name=Ref_GUP538>{{Ref GUP|538}}</ref> | ||
| CD117 | | CD117 | ||
| appearance similar to seminoma | | appearance similar to seminoma | ||
| Line 94: | Line 94: | ||
| Seminoma | | Seminoma | ||
| fried egg cells | | fried egg cells | ||
| fried egg-like cells (central nucleus, clear <br>cytoplasm) with squared-off nuclear <br>membrane, nucleoli, lymphocytic infiltrate, granulomata,<br>syncytiotrophoblastic giant cells<ref>GUP | | fried egg-like cells (central nucleus, clear <br>cytoplasm) with squared-off nuclear <br>membrane, nucleoli, lymphocytic infiltrate, granulomata,<br>syncytiotrophoblastic giant cells<ref name=Ref_GUP542>{{Ref GUP|542}}</ref> | ||
| D2-40 | | D2-40 | ||
| Dysgerminoma | | Dysgerminoma | ||
| Line 201: | Line 201: | ||
***Nucleus has "corners", i.e. it is ''not'' round. | ***Nucleus has "corners", i.e. it is ''not'' round. | ||
*Lymphoctyes common, not essential. | *Lymphoctyes common, not essential. | ||
*May see [[syncytiotrophoblast]]s, AKA ''syncytiotrophoblastic giant cells'' (STGCs).<ref>GUP | *May see [[syncytiotrophoblast]]s, AKA ''syncytiotrophoblastic giant cells'' (STGCs).<ref name=Ref_GUP542>{{Ref GUP|542}}</ref> | ||
**Large + irregular, vesicular nuclei. | **Large + irregular, vesicular nuclei. | ||
**Eosinophilic vacuolated cytoplasm (contains hCG). | **Eosinophilic vacuolated cytoplasm (contains hCG). | ||
| Line 300: | Line 300: | ||
===Microscopy=== | ===Microscopy=== | ||
Features:<ref>GUP | Features:<ref name=Ref_GUP549>{{Ref GUP|549}}</ref> | ||
*Indistinct cell borders | *Indistinct cell borders | ||
*Mitoses - common. | *Mitoses - common. | ||
| Line 411: | Line 411: | ||
===Microscopic=== | ===Microscopic=== | ||
Features:<ref>GUP | Features:<ref name=Ref_GUP581>{{Ref GUP|581}}</ref> | ||
*Vacuolization - ''key feature''. | *Vacuolization - ''key feature''. | ||
*Cytoplasm - clear to eosinophilic. | *Cytoplasm - clear to eosinophilic. | ||