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Difference between revisions of "Testicular metastasis"
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Testicular metastasis (view source)
Revision as of 14:44, 14 December 2016
, 14:44, 14 December 2016wikify
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| Caption = Testis with metastatic prostate carcinoma. [[H&E stain]]. (WC) | | Caption = Testis with metastatic prostate carcinoma. [[H&E stain]]. (WC) | ||
| Synonyms = testicle with metastatic disease | | Synonyms = testicle with metastatic disease | ||
| Micro = atypical cells between seminiferous tubules, negative for [[ | | Micro = atypical cells between seminiferous tubules, negative for [[GCNIS]], +/-lymphovascular invasion | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = | | LMDDx = | ||
| Stains = | | Stains = | ||
| IHC = IHC dependent on primary site (usually OCT4 -ve, AFP -ve, beta-hCG -ve, SALL4 -ve) | | IHC = IHC dependent on primary site (usually OCT4 -ve, AFP -ve, beta-hCG -ve, [[SALL4]] -ve) | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
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==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Lack of [[ | *Lack of [[germ cell neoplasia in situ]] (GCNIS). | ||
*Atypical cells infiltrating between benign-appearing seminiferous tubules. | *Atypical cells infiltrating between benign-appearing seminiferous tubules. | ||
*+/-[[Lymphovascular invasion]]. | *+/-[[Lymphovascular invasion]]. | ||