Talk:Squamous intraepithelial lesion of the uterine cervix

From Libre Pathology
Jump to navigation Jump to search
The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.
UTERINE CERVIX, BIOPSY:
- SQUAMOUS INTRAEPITHELIAL LESION, FAVOUR HIGH-GRADE -- SMALL FOCUS, SEE COMMENT.
- BENIGN ENDOCERVICAL EPITHELIUM PRESENT.

COMMENT:
The cytology has intermediate features.

A p16 immunostain strongly marks the full thickness of the thin (abnormal) squamous
epithelium seen in the plane of section, and a Ki-67 focally shows positive superficial cells. These findings favour the presence of a high-grade squamous intraepithelial lesion (HSIL).

A re-biopsy with close follow-up could be considered.

Idea

UTERINE CERVIX, 12 O'CLOCK, BIOPSY:
- HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION (HSIL).
- VERY SCANT STRIPPED ENDOCERVICAL EPITHELIUM.
- ACUTE AND CHRONIC INFLAMMATION.

COMMENT:
A p16 immunostain marks the full thickness of the squamous epithelium and is 
strong. A Ki-67 immunostain marks a mildly increased number of superficial 
epithelial cells. A   immunostain shows basal staining and superficial 
non-staining in the region of HSIL.
Retrieved from "https://librepathology.org/w/index.php?title=Talk:Squamous_intraepithelial_lesion_of_the_uterine_cervix&oldid=31198"