Difference between revisions of "Syphilis"

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*Classically affects the [[testis]] before the epididymis.<ref name=Ref_WMSP364>{{Ref WMSP|364}}</ref>
*Classically affects the [[testis]] before the epididymis.<ref name=Ref_WMSP364>{{Ref WMSP|364}}</ref>
*Considered one of the [[TORCH infections]].
*Considered one of the [[TORCH infections]].
==Gross==
Aorta:
*Wrinkled intimal surface - "tree bark" appearance.<ref>{{Ref AoGP|80}}</ref>


==Microscopic==
==Microscopic==

Revision as of 01:10, 28 February 2012

Syphilis is the infectious disease caused by Treponema pallidum.

General

Gross

Aorta:

  • Wrinkled intimal surface - "tree bark" appearance.[2]

Microscopic

Features:

  • Plasma cells - key feature.[3]
  • Spirochetes - diagnostic.
  • +/-Granulomas[4] - gumma - in the tertiary phase.[5]


Useful stains:

Image: Dieterle stain - T. pallidum (WC).

See also

References

  1. Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 364. ISBN 978-0781765275.
  2. Rose, Alan G. (2008). Atlas of Gross Pathology with Histologic Correlation (1st ed.). Cambridge University Press. pp. 80. ISBN 978-0521868792.
  3. Brinster, NK. (Nov 2008). "Dermatopathology for the surgical pathologist: a pattern-based approach to the diagnosis of inflammatory skin disorders (part II).". Adv Anat Pathol 15 (6): 350-69. doi:10.1097/PAP.0b013e31818b1ac6. PMID 18948765.
  4. Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 47. ISBN 978-1416054542.
  5. URL: http://pediatrics.aappublications.org/cgi/content/full/104/1/e4. Accessed on: 17 November 2010.