Sudden natural death

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Sudden natural death happens. It must be differentiated from other ways of dying (suicide, homicide, accidental).

By system

Respiratory[1]

Cerebral

  • SUDEP (sudden unexpected death in epilepsy).

Cardiac

Older

  • Atherosclerotic heart disease (ASHD); AKA coronary artery disease (CAD).
  • Hypertensive heart disease - a heart > ~400 g is considered good enough if nothing else is present.[2]

Younger

Notes:

  • The mechanism is usually arrhythmia; this is usually not provable at autopsy.

Detailed cardiac[1]

  • ASHD.
  • Cardiomyopathy.
  • Lymphocytic myocarditis.
  • Floppy mitral valve (MV).
  • Aortic valve stenosis.
  • Congenital cardiac abnormality.
  • Coronary artery dissection.
  • Aortic dissection.
  • Arrhythmia.[3]
    • Long QT syndrome.
    • Brugada syndrome.
    • Short QT syndrome.
    • Catecholaminergic polymorphic ventricular tachycardia (CPVT).
    • Anomalous conduction pathways.
    • Dysplasia of nodal arteries.
    • Atrioventricular node tumour.
    • Sodium channel disease.
    • Idiopathic ventricular fibrillation.

Post-mortem (molecular) testing for arrhythmias:[4]

  • CPVT.
  • Sodium channel disease.
  • Brugada syndrome.

By mechanism

Hemorrhagic[1]

  • Ruptured AAA.
  • Peptic ulcer.
  • Cerebral aneurysm.

See also

Reference

  1. ↑ 1.0 1.1 1.2 de la Grandmaison GL (January 2006). "Is there progress in the autopsy diagnosis of sudden unexpected death in adults?". Forensic Sci. Int. 156 (2-3): 138–44. doi:10.1016/j.forsciint.2004.12.024. PMID 16410164.
  2. ↑ MSP. 29 September 2010.
  3. ↑ URL: http://www.sads.org.uk/causes_of_sads.htm. Accessed on: 29 September 2010.
  4. ↑ MSP. 29 September 2010:
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