Steatocystoma

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Steatocystoma
Diagnosis in short

Steatocystoma. H&E stain.

LM cyst lined by squamous epithelium with a corrugated eosinophilic lining, no granular cell layer
Site skin - see dermal cysts

Syndromes steatocystoma multiplex

Prevalence rare
Prognosis benign

Steatocystoma is a rare benign dermal cyst.

General

  • Benign.
  • Typically adults.
  • Usually on the trunk.
  • May be genetic; known as steatocystoma multiplex.[1]
    • Classically autosomal dominant.[2]

Microscopic

Features:[3]

  • Cyst lined by squamous epithelium with:
    1. Corrugated eosinophilic lining - key feature.
      • Similar appearance to compact keratin (hyperkeratosis).
      • Described as a hyaline cuticle.[4]
    2. No granular cell layer.

Images

www:

See also

References

  1. Online 'Mendelian Inheritance in Man' (OMIM) 184500
  2. URL: http://path.upmc.edu/cases/case674/dx.html. Accessed on: 29 January 2012.
  3. Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 312. ISBN 978-0443066542.
  4. URL: http://path.upmc.edu/cases/case674/dx.html. Accessed on: 29 January 2012.
  5. URL: http://path.upmc.edu/cases/case674.html. Accessed on: 29 January 2012.