Difference between revisions of "Steatocystoma"

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#redirect [[Dermal_cysts#Steatocystoma]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Steatocystoma - very high mag.jpg
| Width      =
| Caption    = Steatocystoma. [[H&E stain]].
| Synonyms  =
| Micro      = cyst lined by squamous epithelium with a corrugated eosinophilic lining, no granular cell layer
| Subtypes  =
| LMDDx      =
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = [[skin]] - see ''[[dermal cysts]]''
| Assdx      =
| Syndromes  = steatocystoma multiplex
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = rare
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    =
| Tx        =
}}
'''Steatocystoma''' is a rare benign [[dermal cyst]].
 
==General==
*Benign.
*Rare.<ref>{{Cite journal  | last1 = Gordon Spratt | first1 = EA. | last2 = Kaplan | first2 = J. | last3 = Patel | first3 = RR. | last4 = Kamino | first4 = H. | last5 = Ramachandran | first5 = SM. | title = Steatocystoma. | journal = Dermatol Online J | volume = 19 | issue = 12 | pages = 20721 | month = Dec | year = 2013 | doi =  | PMID = 24365012 }}</ref>
*Typically adults.
*Usually on the trunk.
*May be genetic; known as ''steatocystoma multiplex''.<ref name=omim184500>{{OMIM|184500}}</ref>
**Classically autosomal dominant.<ref>URL: [http://path.upmc.edu/cases/case674/dx.html http://path.upmc.edu/cases/case674/dx.html]. Accessed on: 29 January 2012.</ref>
 
==Microscopic==
Features:<ref name=Ref_Derm312>{{Ref Derm|312}}</ref>
*Cyst lined by squamous epithelium with:
*#Corrugated eosinophilic lining - '''key feature'''.
*#*Similar appearance to compact keratin (hyperkeratosis).
*#*Described as a ''hyaline cuticle''.<ref>URL: [http://path.upmc.edu/cases/case674/dx.html http://path.upmc.edu/cases/case674/dx.html]. Accessed on: 29 January 2012.</ref>
*#'''No''' granular cell layer.
 
===Images===
<gallery>
Image:SkinTumors-P6260388.JPG | Steatocystoma. (WC)
Image:Steatocystoma_-_low_mag.jpg | Steatocystoma - low mag. (WC/Nephron)
Image:Steatocystoma_-_intermed_mag.jpg | Steatocystoma - intermed. mag. (WC/Nephron)
Image:Steatocystoma_-_high_mag.jpg | Steatocystoma - high mag. (WC/Nephron)
</gallery>
www:
*[http://www.flickr.com/photos/santoshpath/4788590105/in/photostream/ Steatocystoma - low mag. (flickr.com)].
**[http://www.flickr.com/photos/santoshpath/4788590109/ Steatocystoma - high mag. (flickr.com)].
*[http://path.upmc.edu/cases/case674/images/fig03.jpg Steatocystoma (upmc.edu)].<ref>URL: [http://path.upmc.edu/cases/case674.html http://path.upmc.edu/cases/case674.html]. Accessed on: 29 January 2012.</ref>
 
==See also==
*[[Dermal cysts]].
 
==References==
{{Reflist|2}}
 
[[Category:Diagnosis]]
[[Category:Dermal cysts]]

Latest revision as of 22:53, 16 February 2014

Steatocystoma
Diagnosis in short

Steatocystoma. H&E stain.
LM cyst lined by squamous epithelium with a corrugated eosinophilic lining, no granular cell layer
Site skin - see dermal cysts
Syndromes steatocystoma multiplex
Prevalence rare
Prognosis benign

Steatocystoma is a rare benign dermal cyst.

General

  • Benign.
  • Rare.[1]
  • Typically adults.
  • Usually on the trunk.
  • May be genetic; known as steatocystoma multiplex.[2]
    • Classically autosomal dominant.[3]

Microscopic

Features:[4]

  • Cyst lined by squamous epithelium with:
    1. Corrugated eosinophilic lining - key feature.
      • Similar appearance to compact keratin (hyperkeratosis).
      • Described as a hyaline cuticle.[5]
    2. No granular cell layer.

Images

  • Steatocystoma. (WC)

  • Steatocystoma - low mag. (WC/Nephron)

  • Steatocystoma - intermed. mag. (WC/Nephron)

  • Steatocystoma - high mag. (WC/Nephron)

www:

See also

References

  1. ↑ Gordon Spratt, EA.; Kaplan, J.; Patel, RR.; Kamino, H.; Ramachandran, SM. (Dec 2013). "Steatocystoma.". Dermatol Online J 19 (12): 20721. PMID 24365012.
  2. ↑ Online 'Mendelian Inheritance in Man' (OMIM) 184500
  3. ↑ URL: http://path.upmc.edu/cases/case674/dx.html. Accessed on: 29 January 2012.
  4. ↑ Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 312. ISBN 978-0443066542.
  5. ↑ URL: http://path.upmc.edu/cases/case674/dx.html. Accessed on: 29 January 2012.
  6. ↑ URL: http://path.upmc.edu/cases/case674.html. Accessed on: 29 January 2012.
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