Difference between revisions of "Spleen"
Jump to navigation
Jump to search
| Line 36: | Line 36: | ||
*Benign. | *Benign. | ||
Clinical:<ref name=pmid15329769/> | Clinical:<ref name=pmid15329769/><ref name=pmid11547761>{{Cite journal | last1 = Dascalescu | first1 = CM. | last2 = Wendum | first2 = D. | last3 = Gorin | first3 = NC. | title = Littoral-cell angioma as a cause of splenomegaly. | journal = N Engl J Med | volume = 345 | issue = 10 | pages = 772-3 | month = Sep | year = 2001 | doi = 10.1056/NEJM200109063451016 | PMID = 11547761 | url=http://www.nejm.org/doi/full/10.1056/NEJM200109063451016 }}</ref> | ||
*Pyrexia (fever), solitary hypodense lesion on imaging. | *Pyrexia (fever), splenomegaly, weight loss, solitary hypodense lesion on imaging. | ||
Note: | Note: | ||
| Line 46: | Line 46: | ||
Features:<ref name=pmid15329769/> | Features:<ref name=pmid15329769/> | ||
*Anastoming, small vascular channels. | *Anastoming, small vascular channels. | ||
*Cystic spaces. | *Cystic spaces. | ||
**May have papillary projections.<ref name=pmid11547761/> | |||
Images: | Images: | ||
Revision as of 04:16, 25 July 2011
The spleen is a forgotten organ.
Splenic enlargement
- Portal hypertension (e.g. cirrhosis).
- Lymphoma:
- Hairy cell leukemia.
- Splenic marginal zone lymphoma.[1]
- Splenic diffuse red pulp small B cell lymphoma.[2]
- Mononucleosis (EBV infection).
- Hemophagocytic syndrome.[3]
Hyaloserositis
- Properly referred to as hyaloserositis of the spleen.
- Capsule of the spleen is white - resembles sugar-coating; also known as sugar-coated spleen.[4]
- Importance: none - benign.
Image(s):
Mononucleosis
General
- EBV infection.
- Massive splenic enlargement.
Microscopic
Features:
- Atypical lymphoid cells.
Littoral cell angioma of the spleen
- For angioma see vascular malformations.
General
Features:[5]
- Rare.
- Benign.
- Pyrexia (fever), splenomegaly, weight loss, solitary hypodense lesion on imaging.
Note:
Microscopic
Features:[5]
- Anastoming, small vascular channels.
- Cystic spaces.
- May have papillary projections.[6]
Images:
See also
References
- ↑ Bennett, M.; Schechter, GP. (Apr 2010). "Treatment of splenic marginal zone lymphoma: splenectomy versus rituximab.". Semin Hematol 47 (2): 143-7. doi:10.1053/j.seminhematol.2010.01.004. PMID 20350661.
- ↑ Baseggio L, Traverse-Glehen A, Callet-Bauchu E, et al. (March 2011). "Relevance of a scoring system including CD11c expression in the identification of splenic diffuse red pulp small B-cell lymphoma (SRPL)". Hematol Oncol 29 (1): 47–51. doi:10.1002/hon.957. PMID 20677173.
- ↑ Maakaroun, NR.; Moanna, A.; Jacob, JT.; Albrecht, H. (Mar 2010). "Viral infections associated with haemophagocytic syndrome.". Rev Med Virol 20 (2): 93-105. doi:10.1002/rmv.638. PMID 20127750.
- ↑ URL: http://www.drugs.com/dict/sugar-coated-spleen.html. Accessed on: 1 September 2010.
- ↑ 5.0 5.1 5.2 5.3 Tan, YM.; Chuah, KL.; Wong, WK. (Jul 2004). "Littoral cell angioma of the spleen.". Ann Acad Med Singapore 33 (4): 524-6. PMID 15329769. http://www.annals.edu.sg/pdf200408/V33N4p524.pdf.
- ↑ 6.0 6.1 Dascalescu, CM.; Wendum, D.; Gorin, NC. (Sep 2001). "Littoral-cell angioma as a cause of splenomegaly.". N Engl J Med 345 (10): 772-3. doi:10.1056/NEJM200109063451016. PMID 11547761. http://www.nejm.org/doi/full/10.1056/NEJM200109063451016.
- ↑ URL: http://www.merriam-webster.com/dictionary/littoral. Accessed on: 24 July 2011.
- ↑ URL: http://dictionary.reference.com/browse/littoral. Accessed on: 24 July 2011.