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Difference between revisions of "Spindle cell"
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[[Image:Malignant peripheral nerve sheath tumour - very high mag.jpg | thumb| right| Spindle cells in a [[MPNST]]. ([[WC]])]] | [[Image:Malignant peripheral nerve sheath tumour - very high mag.jpg | thumb| right| Spindle cells in a [[MPNST]]. ([[WC]])]] | ||
[[Image:Cutaneous leiomyosarcoma - high mag.jpg | thumb |right| Spindle cells in a [[leiomyosarcoma]]. (WC)]] | |||
'''Spindle cell''' is a histomorphologic descriptor used in [[pathology]]. | '''Spindle cell''' is a histomorphologic descriptor used in [[pathology]]. | ||
A list of spindle cell lesions is found the in the ''[[spindle cell lesions]]'' article. | |||
==Definition== | ==Definition== | ||
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**Image: [http://qcfocus.com/files/Pipe%20Thread%20Taper.jpg Taperred thread (qcfocus.com)]. | **Image: [http://qcfocus.com/files/Pipe%20Thread%20Taper.jpg Taperred thread (qcfocus.com)]. | ||
*Spindle cells can have "pointy" ends (typical for nerves) or "rounded" ends (typical for muscle), i.e. be ellipitcal or vesica piscis. | *Spindle cells can have "pointy" ends (typical for nerves) or "rounded" ends (typical for muscle), i.e. be ellipitcal or vesica piscis. | ||
===Subtyping spindle cells by H&E=== | |||
Spindle cells can often be subtyped based on H&E:<ref name=pmid24406626>{{Cite journal | last1 = Chan | first1 = JK. | title = The wonderful colors of the hematoxylin-eosin stain in diagnostic surgical pathology. | journal = Int J Surg Pathol | volume = 22 | issue = 1 | pages = 12-32 | month = Feb | year = 2014 | doi = 10.1177/1066896913517939 | PMID = 24406626 }}</ref> | |||
*Fibroblast = blue. | |||
*Smooth muscle = deep pink. | |||
*Myofibroblast = purple. | |||
===Images=== | ===Images=== | ||