Difference between revisions of "Spindle cell"

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**Image: [http://qcfocus.com/files/Pipe%20Thread%20Taper.jpg Taperred thread (qcfocus.com)].
**Image: [http://qcfocus.com/files/Pipe%20Thread%20Taper.jpg Taperred thread (qcfocus.com)].
*Spindle cells can have "pointy" ends (typical for nerves) or "rounded" ends (typical for muscle), i.e. be ellipitcal or vesica piscis.
*Spindle cells can have "pointy" ends (typical for nerves) or "rounded" ends (typical for muscle), i.e. be ellipitcal or vesica piscis.
===Subtyping spindle cells by H&E===
Spindle cells can often be subtyped based on H&E:<ref name=pmid24406626>{{Cite journal  | last1 = Chan | first1 = JK. | title = The wonderful colors of the hematoxylin-eosin stain in diagnostic surgical pathology. | journal = Int J Surg Pathol | volume = 22 | issue = 1 | pages = 12-32 | month = Feb | year = 2014 | doi = 10.1177/1066896913517939 | PMID = 24406626 }}</ref>
*Fibroblast = blue.
*Smooth muscle = deep pink.
*Myofibroblast = purple.


===Images===
===Images===

Revision as of 02:41, 26 October 2015

Spindle cells in a MPNST. (WC)

Spindle cell is a histomorphologic descriptor used in pathology.

Definition

It refers to a cell that is tapered at both ends.[1]

Notes:

  • A taper gradually decreases toward one end [of the cross-section or width].[2]
  • Spindle cells can have "pointy" ends (typical for nerves) or "rounded" ends (typical for muscle), i.e. be ellipitcal or vesica piscis.

Subtyping spindle cells by H&E

Spindle cells can often be subtyped based on H&E:[3]

  • Fibroblast = blue.
  • Smooth muscle = deep pink.
  • Myofibroblast = purple.

Images

Shapes

See also

References

  1. URL: http://www.medterms.com/script/main/art.asp?articlekey=25657. Accessed on: 2 February 2011.
  2. URL: http://dictionary.reference.com/browse/taper. Accessed on: 3 February 2011.
  3. Chan, JK. (Feb 2014). "The wonderful colors of the hematoxylin-eosin stain in diagnostic surgical pathology.". Int J Surg Pathol 22 (1): 12-32. doi:10.1177/1066896913517939. PMID 24406626.

External links