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Difference between revisions of "Small cell carcinoma of the urinary bladder"
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Small cell carcinoma of the urinary bladder (view source)
Revision as of 14:07, 30 June 2021
, 14:07, 30 June 2021+SO
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*Synaptophysin +ve. | *Synaptophysin +ve. | ||
*[[CD56]] +ve. | *[[CD56]] +ve. | ||
==Sign out== | |||
<pre> | |||
Urinary Bladder Tumour, Transurethral Resection: | |||
- SMALL CELL CARCINOMA, invades muscularis propria, see comment. | |||
-- Please see synoptic report. | |||
Comment: | |||
The tumour consists of cohesive, moulded, small blue cells with necrosis. There is no definite urothelial differentiation, and no other differentiation to suggest a particular primary site. | |||
The tumour stains as follows: | |||
POSITIVE: CK7 (dot-like moderate, diffuse), chromogranin A (moderate, diffuse), synaptophysin (strong, diffuse), TTF-1 (strong, diffuse). | |||
NEGATIVE: CK20, CD45 (lymphocytes in background), CD20, PSA, p63 (marks benign urothelium). | |||
PROLIFERATION (Ki-67): >90%. | |||
Small cell carcinoma of the urinary bladder is the main consideration, based the anatomical site of the specimen. The findings above should be considered in the context of the imaging and clinical history. | |||
</pre> | |||
==See also== | ==See also== | ||