Difference between revisions of "Sickle cell disease"
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==Spleen== | ==Spleen== | ||
{{Main|Spleen}} | {{Main|Spleen}} | ||
*It may lead to auto infarction - result in hypofunction. | *It may lead to auto [[splenic infarction|infarction]] - result in hypofunction. | ||
**Splenectomy have increased risk from ''polysaccharide encapsulated bacteria'', i.e. Neisseria meningitis, Haemophilus influenzae, and Streptococcus pneumoniae. | **Splenectomy have increased risk from ''polysaccharide encapsulated bacteria'', i.e. Neisseria meningitis, Haemophilus influenzae, and Streptococcus pneumoniae. | ||
Revision as of 02:02, 3 September 2012
Sickle cell disease, also sickle cell anemia, is a heritable haematologic disorder associated with serious pathologies.
Liver
Main article: Liver
Images:
- Sickle cell disease and cirrhosis - intermed. mag. (WC).
- Sickle cell disease and cirrhosis - very high mag. (WC).
Spleen
Main article: Spleen
- It may lead to auto infarction - result in hypofunction.
- Splenectomy have increased risk from polysaccharide encapsulated bacteria, i.e. Neisseria meningitis, Haemophilus influenzae, and Streptococcus pneumoniae.
Gallbladder
Main article: Gallbladder
- Pigment stones.
Kidney
- Renal medullary carcinoma associated with sickle cell trait (heterozygotes for the sickle cell allele).[2]
See also
References
- ↑ Hurtova, M.; Bachir, D.; Lee, K.; Calderaro, J.; Decaens, T.; Kluger, MD.; Zafrani, ES.; Cherqui, D. et al. (Apr 2011). "Transplantation for liver failure in patients with sickle cell disease: challenging but feasible.". Liver Transpl 17 (4): 381-92. doi:10.1002/lt.22257. PMID 21445921.
- ↑ Davis CJ, Mostofi FK, Sesterhenn IA (January 1995). "Renal medullary carcinoma. The seventh sickle cell nephropathy". Am. J. Surg. Pathol. 19 (1): 1–11. PMID 7528470.