Difference between revisions of "Sex cord tumour with annular tubules"

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#redirect [[Ovarian_tumours#Sex_cord_tumour_with_annular_tubules]]
'''Sex cord tumour with annular tubules''', abbreviated '''SCTAT''', is an uncommon sex cord tumour.


It is '''not''' ''sex cord tumour with angulated tubules''.
==General==
*Associated with [[Peutz-Jeghers syndrome]].<ref name=pmid7358344>{{Cite journal  | last1 = Purohit | first1 = RC. | last2 = Alam | first2 = SZ. | title = Sex cord tumour of the ovary with annular tubules (SCTAT). | journal = Histopathology | volume = 4 | issue = 2 | pages = 147-54 | month = Mar | year = 1980 | doi =  | PMID = 7358344 }}</ref>
**Large tumours more likely sporadic.
**Small tumours more likely Peutz-Jeghers syndrome and incidental.
*Usually benign.
**Malignant cases reported.<ref name=pmid10786816>{{Cite journal  | last1 = Lele | first1 = SM. | last2 = Sawh | first2 = RN. | last3 = Zaharopoulos | first3 = P. | last4 = Adesokan | first4 = A. | last5 = Smith | first5 = M. | last6 = Linhart | first6 = JM. | last7 = Arrastia | first7 = CD. | last8 = Krigman | first8 = HR. | title = Malignant ovarian sex cord tumor with annular tubules in a patient with Peutz-Jeghers syndrome: a case report. | journal = Mod Pathol | volume = 13 | issue = 4 | pages = 466-70 | month = Apr | year = 2000 | doi = 10.1038/modpathol.3880079 | PMID = 10786816 }}</ref>
==Microscopic==
Features:
*Well-circumscribed nests of cells with nuclei at the periphery.
*Annular tubules (ring-shaped tubules) with dense hyaline material.
Notes:
*''Annular'' = shape of a ring.<ref>URL: [http://dictionary.reference.com/browse/annular http://dictionary.reference.com/browse/annular]. Accessed on: 6 August 2011.</ref>
*May focally have features of [[Sertoli cell tumour]] or [[granulosa cell tumour]].<ref name=pmid7104978>{{Cite journal  | last1 = Young | first1 = RH. | last2 = Welch | first2 = WR. | last3 = Dickersin | first3 = GR. | last4 = Scully | first4 = RE. | title = Ovarian sex cord tumor with annular tubules: review of 74 cases including 27 with Peutz-Jeghers syndrome and four with adenoma malignum of the cervix. | journal = Cancer | volume = 50 | issue = 7 | pages = 1384-402 | month = Oct | year = 1982 | doi =  | PMID = 7104978 }}
</ref>
DDx:
*Sertoli-Leydig tumour - has double palisading with overlap of the layers.
*[[Granulosa cell tumour]] - have Call-Exner bodies, which don't have a well-defined/solid content.
*[[Brenner tumour]] - [[coffee-bean nuclei]].
===Images===
www:
*[http://www.gfmer.ch/selected_images_v2/detail_list.php?cat1=10&cat2=120&cat3=1015&cat4=3&stype=n SCTAT - image collection (gfmer.ch)].
*[http://www.pathology.cn/bbs/forum.php?mod=viewthread&tid=57445 Possible SCTAT (pathology.cn)].
<gallery>
Image:Sex_cord_tumour_with_annular_tubules_-_intermed_mag.jpg | SCTAT - intermed. mag. (WC)
Image:Sex_cord_tumour_with_annular_tubules_-_high_mag.jpg | SCTAT - high mag. (WC)
Image:Sex_cord_tumour_with_annular_tubules_-_very_high_mag.jpg | SCTAT - very high mag. (WC)
Image:Sex_cord_tumour_with_annular_tubules_-_2_-_very_high_mag.jpg | SCTAT - very high mag. (WC)
</gallery>
==See also==
*[[Ovarian tumours]].
==References==
{{Reflist|2}}
[[Category:Ovarian tumours]]
[[Category:Diagnosis]]
[[Category:Diagnosis]]

Revision as of 15:24, 11 January 2014

Sex cord tumour with annular tubules, abbreviated SCTAT, is an uncommon sex cord tumour.

It is not sex cord tumour with angulated tubules.

General

  • Associated with Peutz-Jeghers syndrome.[1]
    • Large tumours more likely sporadic.
    • Small tumours more likely Peutz-Jeghers syndrome and incidental.
  • Usually benign.
    • Malignant cases reported.[2]

Microscopic

Features:

  • Well-circumscribed nests of cells with nuclei at the periphery.
  • Annular tubules (ring-shaped tubules) with dense hyaline material.

Notes:

DDx:

Images

www:

  • SCTAT - intermed. mag. (WC)

  • SCTAT - high mag. (WC)

  • SCTAT - very high mag. (WC)

  • SCTAT - very high mag. (WC)

See also

References

  1. ↑ Purohit, RC.; Alam, SZ. (Mar 1980). "Sex cord tumour of the ovary with annular tubules (SCTAT).". Histopathology 4 (2): 147-54. PMID 7358344.
  2. ↑ Lele, SM.; Sawh, RN.; Zaharopoulos, P.; Adesokan, A.; Smith, M.; Linhart, JM.; Arrastia, CD.; Krigman, HR. (Apr 2000). "Malignant ovarian sex cord tumor with annular tubules in a patient with Peutz-Jeghers syndrome: a case report.". Mod Pathol 13 (4): 466-70. doi:10.1038/modpathol.3880079. PMID 10786816.
  3. ↑ URL: http://dictionary.reference.com/browse/annular. Accessed on: 6 August 2011.
  4. ↑ Young, RH.; Welch, WR.; Dickersin, GR.; Scully, RE. (Oct 1982). "Ovarian sex cord tumor with annular tubules: review of 74 cases including 27 with Peutz-Jeghers syndrome and four with adenoma malignum of the cervix.". Cancer 50 (7): 1384-402. PMID 7104978.
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