Difference between revisions of "Sertoli cell tumour"

Sertoli cell tumour (view source)

127 bytes added , 10:51, 13 September 2023

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 *Alpha-inhibin +ve (~95% of cases<ref name=pmid17721194/>).
 *Calretiin +ve (~55% of cases<ref name=pmid17721194/>).
-*Beta-catenin (nuclear +ve).<ref>{{cite journal |authors=Zhang C, Ulbright TM |title=Nuclear Localization of β-Catenin in Sertoli Cell Tumors and Other Sex Cord-Stromal Tumors of the Testis: An Immunohistochemical Study of 87 Cases |journal=Am J Surg Pathol |volume=39 |issue=10 |pages=1390–4 |date=October 2015 |pmid=26034868 |doi=10.1097/PAS.0000000000000455 |url=}}</ref>
+*Beta-catenin +ve (nuclear).<ref>{{cite journal |authors=Zhang C, Ulbright TM |title=Nuclear Localization of β-Catenin in Sertoli Cell Tumors and Other Sex Cord-Stromal Tumors of the Testis: An Immunohistochemical Study of 87 Cases |journal=Am J Surg Pathol |volume=39 |issue=10 |pages=1390–4 |date=October 2015 |pmid=26034868 |doi=10.1097/PAS.0000000000000455 |url=}}</ref>
+**Negative beta-catenin should make one consider other diagnoses.{{fact}}
+**May be negative in malignant sertoli cell tumours.
 Others: