Sclerosing mucoepidermoid carcinoma with eosinophilia
Jump to navigation
Jump to search
The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.
Sclerosing mucoepidermoid carcinoma with eosinophilia is an extremely rare tumour of the thyroid gland.
General
Associated with:
- Chronic thyroiditis, e.g. Hashimoto's thyroiditis.
- Papillary thyroid carcinoma.
Microscopic
Features:
- Mucous cells
- Squamoid differentiation.
DDx:
Stains
- Mucin stains +ve.
IHC
- TTF-1 +ve
- Thyroglobulin -ve.
- PAX8 +ve.
- Calcitonin -ve.
Molecular
- Negative for MAML2 rearrangements.[1]
See also
References
- ↑ Shah, AA.; La Fortune, K.; Miller, C.; Mills, SE.; Baloch, Z.; LiVolsi, V.; Dacic, S.; Mahaffey, AL. et al. (Mar 2017). "Thyroid sclerosing mucoepidermoid carcinoma with eosinophilia: a clinicopathologic and molecular analysis of a distinct entity.". Mod Pathol 30 (3): 329-339. doi:10.1038/modpathol.2016.180. PMID 27910944.