Difference between revisions of "Salivary glands"

Salivary glands (view source)

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 ==Acinic cell adenocarcinoma==
 *Abbreviated ''AcCC''.
-*Common malignant neoplasm of salivary gland.
+===General===
+*Malignant neoplasm of salivary gland arising from acinic cells.
+*The relative prevalence of the neoplasm in the various salivary gland reflects the abundance of acinic cells: parotid gland (~80%) > minor salivary glands (~17%) > submandibular glands (~3%).
+*Affects wide age range -- including children.
+===Gross===
+*Tan or reddish.
+===Microscopic===
 Features:
-*Psammoma bodies(?).
+*Sheets of cells.
 *Abundant cytoplasm.
-*Stipled chromatin.
+*Stippled chromatin.
-*Acinar architecture (islands of cells).
+*+/-Peri-tumoural lymphocytes.
+Notes:
+*Adipose tissue -- present in the salivary glands -- is absent in AcCC.
 Memory device:
 *AcCC - lots of "C"s - '''c'''hromatin stipled, '''c'''ytoplasm generous.
+Images:
+*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20080802170246445 AcCC (surgicalpathologyatlas.com)].
+*[http://www.brown.edu/Courses/Digital_Path/systemic_path/hn/acinic.html AcCC (brown.edu)].
+*[http://www.aciniccell.org/acc_images14.html AcCC (aciniccell.org)] - image collection.
+====Subtypes====
+*Oncocytic variant.
+*Clear cell variant.
+*Papillary cystic variant.
+===Stains/IHC===
+*PAS +ve.
+*PAS-D +ve.
 ==Adenoid cystic carcinoma==