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Difference between revisions of "Renal transplant pathology"
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Renal transplant pathology (view source)
Revision as of 18:07, 4 November 2011
, 18:07, 4 November 2011→Calcineurin-inhibitor toxicity
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==Calcineurin-inhibitor toxicity== | ==Calcineurin-inhibitor toxicity== | ||
*Calcineurin-inhibitors (e.g. cyclosporine,<ref name=pmid10354295>{{cite journal |author=Zarifian A, Meleg-Smith S, O'donovan R, Tesi RJ, Batuman V |title=Cyclosporine-associated thrombotic microangiopathy in renal allografts |journal=Kidney Int. |volume=55 |issue=6 |pages=2457–66 |year=1999 |month=June |pmid=10354295 |doi=10.1046/j.1523-1755.1999.00492.x |url=}}</ref> | *Calcineurin-inhibitors (e.g. cyclosporine,<ref name=pmid10354295>{{cite journal |author=Zarifian A, Meleg-Smith S, O'donovan R, Tesi RJ, Batuman V |title=Cyclosporine-associated thrombotic microangiopathy in renal allografts |journal=Kidney Int. |volume=55 |issue=6 |pages=2457–66 |year=1999 |month=June |pmid=10354295 |doi=10.1046/j.1523-1755.1999.00492.x |url=}}</ref> tacrolimus<ref name=Ref_FoRP203>{{Ref FoRP|203}}</ref>) toxicity can induce a [[thrombotic microangiopathy]]. | ||
===Microscopic=== | |||
Features: | |||
*Hyaline arteriopathy with a peripheral and nodular distribution (chronic toxicity). | *Hyaline arteriopathy with a peripheral and nodular distribution (chronic toxicity). | ||