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Difference between revisions of "Renal mucinous tubular and spindle cell carcinoma"
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Renal mucinous tubular and spindle cell carcinoma (view source)
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'''Renal mucinous tubular and spindle cell carcinoma''', abbreviated '''RMTSCC''', is a rare malignant epithelial neoplasm of the [[kidney]]. | |||
It is also known as '''renal mucinous tubular spindle cell carcinoma''' and | |||
'''mucinous tubular and spindle cell carcinoma of the kidney'''.<ref name=pmid16258504>{{Cite journal | last1 = Brandal | first1 = P. | last2 = Lie | first2 = AK. | last3 = Bassarova | first3 = A. | last4 = Svindland | first4 = A. | last5 = Risberg | first5 = B. | last6 = Danielsen | first6 = H. | last7 = Heim | first7 = S. | title = Genomic aberrations in mucinous tubular and spindle cell renal cell carcinomas. | journal = Mod Pathol | volume = 19 | issue = 2 | pages = 186-94 | month = Feb | year = 2006 | doi = 10.1038/modpathol.3800499 | PMID = 16258504 }}</ref> | |||
==General== | |||
*Rare.<ref name=pmid19494850>{{Cite journal | last1 = Srigley | first1 = JR. | last2 = Delahunt | first2 = B. | title = Uncommon and recently described renal carcinomas. | journal = Mod Pathol | volume = 22 Suppl 2 | issue = | pages = S2-S23 | month = Jun | year = 2009 | doi = 10.1038/modpathol.2009.70 | PMID = 19494850 }}</ref> | |||
*Accepted by WHO in 2004 as a separate entity.<ref name=pmid19805959>{{cite journal |author=Geramizadeh B, Salehipour M, Moradi A |title=Mucinous tubular and spindle cell carcinoma of kidney: a rare case report and review of the literature |journal=Indian J Pathol Microbiol |volume=52 |issue=4 |pages=514–6 |year=2009 |pmid=19805959 |doi=10.4103/0377-4929.56144 |url=}}</ref> | |||
*Relatively good prognosis. | |||
==Microscopic== | |||
Features:<ref name=pmid19066686>{{cite journal |author=Trabelsi A, Stita W, Yacoubi MT, Rammeh S, Hmissa S, Korbi S |title=Renal mucinous tubular and spindle cell carcinoma |journal=Can Urol Assoc J |volume=2 |issue=6 |pages=635–6 |year=2008 |month=December |pmid=19066686 |pmc=2593603 |doi= |url=}}</ref> | |||
*Mucin (foamy macrophages) - may be scant. | |||
*Spindle cells - '''key feature'''. | |||
DDx: | |||
*Sarcomatoid [[papillary renal cell carcinoma]].<ref name=pmid18941398>{{cite journal |author=Dhillon J, Amin MB, Selbs E, Turi GK, Paner GP, Reuter VE |title=Mucinous tubular and spindle cell carcinoma of the kidney with sarcomatoid change |journal=Am. J. Surg. Pathol. |volume=33 |issue=1 |pages=44–9 |year=2009 |month=January |pmid=18941398 |doi=10.1097/PAS.0b013e3181829ed5 |url=}}</ref> | |||
*[[Renal mucinous tubular and spindle cell carcinoma]]. | |||
===Images=== | |||
www: | |||
*[http://moon.ouhsc.edu/kfung/jty1/OPAQ/PathQuiz-Answer/K1A001-PQ01-Ans.htm RMTSCC (ouhsc.edu)]. | |||
*[http://www.cttr.org/large/02146b.jpg RMTSCC (cttr.org)].<ref>URL: [http://www.cttr.org/cms/?p=1406 http://www.cttr.org/cms/?p=1406]. Accessed on: 28 February 2014.</ref> | |||
==IHC== | |||
Features:<ref name=pmid16231179>{{cite journal |author=Ferlicot S, Allory Y, Compérat E, ''et al.'' |title=Mucinous tubular and spindle cell carcinoma: a report of 15 cases and a review of the literature |journal=Virchows Arch. |volume=447 |issue=6 |pages=978–83 |year=2005 |month=December |pmid=16231179 |doi=10.1007/s00428-005-0036-x |url=}}</ref> | |||
*CD10 -ve. | |||
*AE1/AE3 +ve. | |||
*AMACR +ve. | |||
*CK7 +ve. | |||
==See also== | |||
*[[Renal tumours]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Renal tumours]] | |||