Difference between revisions of "Radiation colitis"
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'''Radiation colitis''' is inflammation of the [[colon]] due to radiation. | '''Radiation colitis''' is inflammation of the [[colon]] due to radiation. | ||
==General== | |||
*Diagnosis should be supported by clinical history. | |||
Cause of colitides: | |||
*IBD. | |||
*Infection. | |||
*Ischemia. | |||
*Radiation. | |||
==Gross== | |||
*Superficial bowel wall injury - shallow ulceration.<ref name=pmid9378391/> | |||
==Microscopic== | ==Microscopic== | ||
| Line 9: | Line 21: | ||
*Submucosa edema with neutrophilic infiltrate. | *Submucosa edema with neutrophilic infiltrate. | ||
*+/-Fibrin thrombi. | *+/-Fibrin thrombi. | ||
DDx: | |||
*[[Ischemic colitis]]. | |||
*[[Inflammatory bowel disease]]. | |||
*Infectious colitis. | |||
Image: | Image: | ||
Revision as of 02:14, 22 February 2013
Radiation colitis is inflammation of the colon due to radiation.
General
- Diagnosis should be supported by clinical history.
Cause of colitides:
- IBD.
- Infection.
- Ischemia.
- Radiation.
Gross
- Superficial bowel wall injury - shallow ulceration.[1]
Microscopic
Features - acute:[1]
- Mucosal changes:
- Necrosis of epithelium.
- "Ghost cells" = cells without nuclei.
- Hemorrhage.
- Necrosis of epithelium.
- Submucosa edema with neutrophilic infiltrate.
- +/-Fibrin thrombi.
DDx:
- Ischemic colitis.
- Inflammatory bowel disease.
- Infectious colitis.
Image:
