Difference between revisions of "RCC (immunostain)"

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(Created page with "'''RCC''' is a common immunostain. It has moderate sensitivity (72%) and specificity (79%) for renal cell carcinoma.<ref>{{Cite journal | last1 = Bakshi | first1 = N...")
 
 
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'''RCC''' is a common [[immunostain]].
'''RCC''' is a common [[immunostain]].


It has moderate sensitivity (72%) and specificity (79%) for [[renal cell carcinoma]].<ref>{{Cite journal  | last1 = Bakshi | first1 = N. | last2 = Kunju | first2 = LP. | last3 = Giordano | first3 = T. | last4 = Shah | first4 = RB. | title = Expression of renal cell carcinoma antigen (RCC) in renal epithelial and nonrenal tumors: diagnostic Implications. | journal = Appl Immunohistochem Mol Morphol | volume = 15 | issue = 3 | pages = 310-5 | month = Sep | year = 2007 | doi = 10.1097/01.pai.0000213144.70148.8e | PMID = 17721277 }}</ref>
It has moderate [[sensitivity]] (72%) and [[specificity]] (79%) for [[renal cell carcinoma]].<ref name=pmid17721277>{{Cite journal  | last1 = Bakshi | first1 = N. | last2 = Kunju | first2 = LP. | last3 = Giordano | first3 = T. | last4 = Shah | first4 = RB. | title = Expression of renal cell carcinoma antigen (RCC) in renal epithelial and nonrenal tumors: diagnostic Implications. | journal = Appl Immunohistochem Mol Morphol | volume = 15 | issue = 3 | pages = 310-5 | month = Sep | year = 2007 | doi = 10.1097/01.pai.0000213144.70148.8e | PMID = 17721277 }}</ref> In a [[metastasis|metastatic]] setting its sensitivity is 40%.<ref name=pmid17721277/>
 
==Negative==
*[[Hepatocellular carcinoma]].<ref name=pmid16280664>{{Cite journal  | last1 = Pan | first1 = CC. | last2 = Chen | first2 = PC. | last3 = Tsay | first3 = SH. | last4 = Ho | first4 = DM. | title = Differential immunoprofiles of hepatocellular carcinoma, renal cell carcinoma, and adrenocortical carcinoma: a systemic immunohistochemical survey using tissue array technique. | journal = Appl Immunohistochem Mol Morphol | volume = 13 | issue = 4 | pages = 347-52 | month = Dec | year = 2005 | doi =  | PMID = 16280664 }}</ref>
*[[Adrenal cortical carcinoma]].<ref name=pmid16280664/>
 
==See also==
*[[Carbonic anhydrase IX]].


==References==
==References==

Latest revision as of 04:21, 5 January 2018

RCC is a common immunostain.

It has moderate sensitivity (72%) and specificity (79%) for renal cell carcinoma.[1] In a metastatic setting its sensitivity is 40%.[1]

Negative

See also

References

  1. 1.0 1.1 Bakshi, N.; Kunju, LP.; Giordano, T.; Shah, RB. (Sep 2007). "Expression of renal cell carcinoma antigen (RCC) in renal epithelial and nonrenal tumors: diagnostic Implications.". Appl Immunohistochem Mol Morphol 15 (3): 310-5. doi:10.1097/01.pai.0000213144.70148.8e. PMID 17721277.
  2. 2.0 2.1 Pan, CC.; Chen, PC.; Tsay, SH.; Ho, DM. (Dec 2005). "Differential immunoprofiles of hepatocellular carcinoma, renal cell carcinoma, and adrenocortical carcinoma: a systemic immunohistochemical survey using tissue array technique.". Appl Immunohistochem Mol Morphol 13 (4): 347-52. PMID 16280664.