Difference between revisions of "Pulmonary neuroendocrine cell hyperplasia"

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{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      =
| Width      =
| Caption    =
| Synonyms  =
| Micro      = proliferation of neuroendocrine cells confined by the basement membrane of the bronchus.
| Subtypes  =
| LMDDx      = [[carcinoid tumourlet]], [[diffuse idiopathic pulmonary neuroendocrine cell hyperplasia]], [[pulmonary meningothelial-like nodule]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = [[lung]]
| Assdx      =
| Syndromes  = if diffuse ''[[diffuse idiopathic pulmonary neuroendocrine cell hyperplasia]] (DIPNECH)''
| Clinicalhx =
| Signs      =
| Symptoms  = none
| Prevalence = very common
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    =
| Tx        = none required
}}
'''Pulmonary neuroendocrine cell hyperplasia''' is a proliferation of neuroendocrine cells confined by the bronchial basement membrane.
'''Pulmonary neuroendocrine cell hyperplasia''' is a proliferation of neuroendocrine cells confined by the bronchial basement membrane.


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DDx:
DDx:
*[[Carcinoid tumourlet]] - extends beyond the basement membrane and less than 5 mm in maximal dimension.
*[[Carcinoid tumourlet]] - extends beyond the basement membrane and less than 5 mm in maximal dimension.
*[[Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia]].
*[[Pulmonary meningothelial-like nodule]].


==See also==
==See also==

Revision as of 01:38, 30 September 2015

Pulmonary neuroendocrine cell hyperplasia
Diagnosis in short

LM proliferation of neuroendocrine cells confined by the basement membrane of the bronchus.
LM DDx carcinoid tumourlet, diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, pulmonary meningothelial-like nodule
Site lung

Syndromes if diffuse diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH)

Symptoms none
Prevalence very common
Prognosis benign
Treatment none required

Pulmonary neuroendocrine cell hyperplasia is a proliferation of neuroendocrine cells confined by the bronchial basement membrane.

General

Microscopic

Features:

  • Proliferation of neuroendocrine cells - confined by the basement membrane of the bronchus.[1]
    • Salt and pepper chromatin.

Note:

  • They often project into the airway.

DDx:

See also

References

  1. Koo, CW.; Baliff, JP.; Torigian, DA.; Litzky, LA.; Gefter, WB.; Akers, SR. (Sep 2010). "Spectrum of pulmonary neuroendocrine cell proliferation: diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, tumorlet, and carcinoids.". AJR Am J Roentgenol 195 (3): 661-8. doi:10.2214/AJR.09.3811. PMID 20729444.