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Difference between revisions of "Pulmonary cytopathology"
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→Adequacy criteria: rework
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==Adequacy criteria== | ==Adequacy criteria== | ||
There is a proposed standard for EBUS specimens:<ref name=pmid22246929>{{Cite journal | last1 = Nayak | first1 = A. | last2 = Sugrue | first2 = C. | last3 = Koenig | first3 = S. | last4 = Wasserman | first4 = PG. | last5 = Hoda | first5 = S. | last6 = Morgenstern | first6 = NJ. | title = Endobronchial ultrasound-guided transbronchial needle aspirate (EBUS-TBNA): a proposal for on-site adequacy criteria. | journal = Diagn Cytopathol | volume = 40 | issue = 2 | pages = 128-37 | month = Feb | year = 2012 | doi = 10.1002/dc.21517 | PMID = 22246929 }}</ref> | There is a proposed standard for EBUS specimens:<ref name=pmid22246929>{{Cite journal | last1 = Nayak | first1 = A. | last2 = Sugrue | first2 = C. | last3 = Koenig | first3 = S. | last4 = Wasserman | first4 = PG. | last5 = Hoda | first5 = S. | last6 = Morgenstern | first6 = NJ. | title = Endobronchial ultrasound-guided transbronchial needle aspirate (EBUS-TBNA): a proposal for on-site adequacy criteria. | journal = Diagn Cytopathol | volume = 40 | issue = 2 | pages = 128-37 | month = Feb | year = 2012 | doi = 10.1002/dc.21517 | PMID = 22246929 }}</ref> | ||
*> 5 low power fields (×10 objective) with >= 100 lymphocytes and < 2 groups of bronchial cells. | *> 5 low power fields (×10 objective) with >= 100 lymphocytes and < 2 groups of bronchial cells. | ||
There is no generally accepted standard for bronchial brushings, washes and lavages. | Other specimen types (brushings, washes and lavages): | ||
*One should see pulmonary macrophages (large cells with bubbly green/brown cytoplasm, eccentric reniform nucleus). | |||
**Ciliated cells may be from the nasopharynx - not proof of lung parenchymal tissue. | |||
There is no generally accepted standard for bronchial brushings, washes and lavages. A house standard at a larger teaching centre is:<ref>UHN PCY50001.08 P.11.</ref> | |||
*Sputum: >= 10 pulmonary macrophages. | *Sputum: >= 10 pulmonary macrophages. | ||