Programmed death-ligand 1

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Programmed death-ligand 1, commonly abbreviated PD-L1, is protein with an important role in immune system regulation, and thus cancer aggressiveness.

It is also known as CD274.[1]

PD-L1 antibodies are being used to treat:[2]

See also

References

  1. Online 'Mendelian Inheritance in Man' (OMIM) 605402
  2. Gandini, S.; Massi, D.; Mandalà, M. (Apr 2016). "PD-L1 expression in cancer patients receiving anti PD-1/PD-L1 antibodies: A systematic review and meta-analysis.". Crit Rev Oncol Hematol 100: 88-98. doi:10.1016/j.critrevonc.2016.02.001. PMID 26895815.